Nopol

Nopol

SCHEMBL114153

CC1(C)C2CC=C(CCO)C1C2

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.55
KDM4E B2RXH2 1/20 0.55
HTT P42858 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
KCNH2 Q12809 1/20 0.54
MAPK1 P28482 2/20 0.53
CXCR3 P49682 16/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nopol SCHEMBL7760931 1.00 TSHR (0.55) TSHRKDM4EHTTTDP1KCNH2
Nopol SCHEMBL5309650 1.00 TSHR (0.55) TSHRKDM4EHTTTDP1KCNH2
Nopol SCHEMBL9723502 1.00 TSHR (0.55) TSHRKDM4EHTTTDP1KCNH2
Nopol SCHEMBL17187721 1.00 TSHR (0.55) TSHRKDM4EHTTTDP1KCNH2
Nopol SCHEMBL10687292 1.00 TSHR (0.55) TSHRKDM4EHTTTDP1KCNH2
Nopol SCHEMBL8610441 1.00 TSHR (0.55) TSHRKDM4EHTTTDP1KCNH2
Nopol SCHEMBL2302936 0.97 KCNH2 (0.55) TSHRKDM4EHTTTDP1KCNH2
Nopol SCHEMBL7925157 0.95 KCNH2 (0.53) TSHRKDM4EHTTTDP1KCNH2
SCHEMBL31033376 0.90 TSHR (0.52) TSHRKDM4EHTTTDP1KCNH2
SCHEMBL31033380 0.90 TSHR (0.52) TSHRKDM4EHTTTDP1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4196 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025108540-A1 5-METHYLCYCLOHEXANOLS AND DERIVATIVES AS FRAGRANCES SYMRISE AG (DE) 2025-05-30 WO claimed
CN-111051483-B Esters and ethers of 2, 4-tetramethyl cyclobutane-1, 3-diol as fragrance chemicals 巴斯夫欧洲公司 2025-01-24 CN claimed
US-12187978-B2 Use of (3-acetoxy-2,2-dimethyl-propyl) acetate in combination with (3-hydroxy-2,2-dimethyl-propyl) acetate as an aroma chemical BASF SE (DE) 2025-01-07 US claimed
EP-4458923-A2 POLYELECTROLYTE-LAYER FORMING BLOCK COPOLYMERS AND COMPOSITIONS AND USED THEREOF SPECIALTY OPERATIONS FRANCE (FR) 2024-11-06 EP claimed
US-12128640-B1 Process for increasing hydrophobicity of articles made of polyolefins TOTALENERGIES ONETECH (FR) 2024-10-29 US claimed
US-20240336023-A1 PROCESS FOR INCREASING HYDROPHOBICITY OF ARTICLES MADE OF POLYOLEFINS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2024-10-10 US claimed
EP-3490389-B1 FRAGRANCE AND FLAVOR COMPOSITIONS CONTAINING ISOMERIC ALKADIENYL ESTERS BEDOUKIAN RES INC (US) 2024-09-25 EP claimed
EP-4429870-A1 PROCESS FOR INCREASING HYDROPHOBICITY OF ARTICLES MADE OF POLYOLEFINS TotalEnergies OneTech (FR) 2024-09-18 EP claimed
CN-115286527-B Preparation method and application of nopic acid amide compounds 南京林业大学 2024-09-13 CN claimed
CN-117820257-A Preparation method of pinaverium bromide intermediate with high cis-isomer content 成都倍特药业股份有限公司 2024-04-05 CN claimed
EP-0175850-B1 DERIVATIVE OF CYCLOHEXENEMETHANOL HAVING A MUCOSECRETOLYTIC ACTIVITY, PROCESS FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME CAMILLO CORVI S.p.A. (IT) 1989-01-18 EP claimed
US-4784793-A FERROELECTRIC SMECTIC MIXTURE FOR ELECTROOPTICAL DISPLAY THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) 1988-11-15 US claimed
EP-0155040-B1 MENTHENE SULPHONATES AND THE HYDROGENATED DERIVATIVES THEREOF UNILEVER N.V. (NL) 1988-04-27 EP claimed
EP-0258298-A1 LIQUID CRYSTAL COMPOUNDS CONTAINING TWO OR MORE CHIRAL CENTERS. SECR DEFENCE BRIT (GB) 1988-03-09 EP claimed
WO-1987004705-A2 LIQUID CRYSTAL COMPOUNDS CONTAINING TWO OR MORE CHIRAL CENTERS THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNI (GB) 1987-08-13 WO claimed
EP-0211030-A1 Ferro-electric smectic liquid crystal materials based on terpenoid derivatives. SECR DEFENCE BRIT (GB) 1987-02-25 EP claimed
CN-86101036-A Contain the liquid crystal material of terpenoid compound derivatives and the device of this material 1986-12-03 CN claimed
WO-1986004328-A1 TERPENOID DERIVATIVES AND LIQUID CRYSTAL MATERIALS AND DEVICES CONTAINING THEM THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNI (GB) 1986-07-31 WO claimed
EP-0155040-A2 Menthene sulphonates and the hydrogenated derivatives thereof UNILEVER N.V. (NL) 1985-09-18 EP claimed
EP-0151941-A2 Epoxidation of olefinic alcohols Union Camp Corporation (US) 1985-08-21 EP claimed