Nopol

Nopol

SCHEMBL7760931

CC1(C)[C@H]2CC=C(CCO)[C@@H]1C2

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.55
KDM4E B2RXH2 1/20 0.55
HTT P42858 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
KCNH2 Q12809 1/20 0.54
MAPK1 P28482 2/20 0.53
CXCR3 P49682 16/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nopol SCHEMBL5309650 1.00 TSHR (0.55) TSHRKDM4EHTTTDP1KCNH2
Nopol SCHEMBL9723502 1.00 TSHR (0.55) TSHRKDM4EHTTTDP1KCNH2
Nopol SCHEMBL17187721 1.00 TSHR (0.55) TSHRKDM4EHTTTDP1KCNH2
Nopol SCHEMBL10687292 1.00 TSHR (0.55) TSHRKDM4EHTTTDP1KCNH2
Nopol SCHEMBL8610441 1.00 TSHR (0.55) TSHRKDM4EHTTTDP1KCNH2
Nopol SCHEMBL114153 1.00 TSHR (0.55) TSHRKDM4EHTTTDP1KCNH2
Nopol SCHEMBL2302936 0.97 KCNH2 (0.55) TSHRKDM4EHTTTDP1KCNH2
Nopol SCHEMBL7925157 0.95 KCNH2 (0.53) TSHRKDM4EHTTTDP1KCNH2
SCHEMBL31033376 0.90 TSHR (0.52) TSHRKDM4EHTTTDP1KCNH2
SCHEMBL31033380 0.90 TSHR (0.52) TSHRKDM4EHTTTDP1KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119638666-A 1, 3-Dithiane substituted cyclobutene derivative and preparation method and application thereof 兰州大学 2025-03-18 CN claimed
WO-2001079212-A1 SILICON DERIVATIVES OF FRAGRANT, FLAVOURING AND MEDICINAL SUBSTANCES KIREEV VYACHESLAV VASILIEVICH (RU) 2001-10-25 WO claimed
US-12606747-B2 Surfactant SPHERE FLUIDICS LIMITED (GB) 2026-04-21 US disclosed
US-12365649-B2 Process for the preparation of brivaracetam ALIVUS LIFE SCIENCES LIMITED (IN) 2025-07-22 US disclosed
CN-120118001-A Aerobic nitriding method for olefin compounds 北京大学 2025-06-10 CN disclosed
CN-119638666-A 1, 3-Dithiane substituted cyclobutene derivative and preparation method and application thereof 兰州大学 2025-03-18 CN disclosed
WO-2024175905-A1 DIMER COMPOUNDS Kesmalea Therapeutics Limited (GB) 2024-08-29 WO disclosed
EP-4146379-B1 SURFACTANTS BASED ON PERFLUOROPOLYETHERS OR FLUOROCARBONS SPHERE FLUIDICS LTD (GB) 2024-06-26 EP disclosed
US-20240010618-A1 PROCESS FOR THE PREPARATION OF BRIVARACETAM ALIVUS LIFE SCIENCES LIMITED (IN) 2024-01-11 US disclosed
EP-2775839-B1 METHODS FOR ASSESSING REPELLANT QUALITY OF ORGANIC MATERIALS AND METHODS AND COMPOSITIONS FOR REPELLING ARTHROPODS UNIV CALIFORNIA (US) 2023-12-06 EP disclosed
US-20230193137-A1 Surfactant SPHERE FLUIDICS LIMITED (GB) 2023-06-22 US disclosed
WO-2014001092-A1 ANTIMICROBIAL COMPOSITION UNILEVER N.V. (NL) 2014-01-03 WO disclosed
WO-2008092981-A1 NOVEL MOLECULE WITH SANDALWOOD FRAGRANCE, METHOD FOR PREPARATION THEREOF AND USE THEREOF AS AN ODORANT UNIVERSIDAD DE JAÉN (ES) 2008-08-07 WO disclosed
US-7390926-B2 Process for the diastereoselective alkylation of an ether oxime of the compound nopinone and novel intermediates for the synthesis of diastereospecific 2-amino-nopinone derivatives substituted on carbon 3 ZACH SYSTEM (IT) 2008-06-24 US disclosed
US-7390926-B2 Process for the diastereoselective alkylation of an ether oxime of the compound nopinone and novel intermediates for the synthesis of diastereospecific 2-amino-nopinone derivatives substituted on carbon 3 ZACH SYSTEM (IT) 2008-06-24 US disclosed
US-20070225516-A1 Process for the diastereoselective alkylation of an ether oxime of the compound nopinone and novel intermediates for the synthesis of diastereospecific 2-amino-nopinone derivatives substituted on carbon 3 PPG-SIPSY (FR) 2007-09-27 US disclosed
US-20070225516-A1 Process for the diastereoselective alkylation of an ether oxime of the compound nopinone and novel intermediates for the synthesis of diastereospecific 2-amino-nopinone derivatives substituted on carbon 3 PPG-SIPSY (FR) 2007-09-27 US disclosed
EP-0406742-B1 PROCESS FOR THE PREPARATION OF CIS-DIHYDRONOPOL Kali-Chemie Pharma GmbH (DE) 1993-04-21 EP disclosed
US-5175347-A Hydogenation of a ester compound in presence of hydrogen using solid catalyst KALI-CHEMIE PHARMA GMBH (DE) 1992-12-29 US disclosed
US-4424374-A Bicycloheptane derivatives MAY & BAKER LIMITED (GB) 1984-01-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12606747-B2 Surfactant SGMS1, SGMS2, AQP1 TSHR 948/4885KDM4E 3302/4885HTT 4276/4885
US-20070225516-A1 Process for the diastereoselective alkylation of an ether oxime of the compound nopinone and novel intermediates for the synthesis of diastereospecific 2-amino-nopinone derivatives substituted on carbon 3 NOP2, NOP10, NOP56 TSHR 2265/4885KDM4E 1677/4885HTT 4778/4885
US-12365649-B2 Process for the preparation of brivaracetam CYP2C19, CYP2B6, POR TSHR 865/4885KDM4E 1365/4885HTT 3909/4885
US-20240010618-A1 PROCESS FOR THE PREPARATION OF BRIVARACETAM CYP2C19, CYP2B6, POR TSHR 865/4885KDM4E 1365/4885HTT 3909/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.