Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD1 | P21728 | 2/20 | 0.47 |
| ▸ | DRD5 | P21918 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | METAP1 | P53582 | 1/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.45 |
| ▸ | MIF | P14174 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2204112 | 0.83 | MEN1 (0.62) | DRD2DRD1DRD5DRD3HTR2A | |
| SCHEMBL15889328 | 0.79 | DRD1 (0.45) | DRD2DRD1DRD5DRD3HTR2A | |
| SCHEMBL29438671 | 0.79 | PRMT5 (0.51) | DRD2DRD1DRD3PRMT5WDR77 | |
| SCHEMBL471627 | 0.79 | PRMT5 (0.51) | DRD2DRD1DRD3PRMT5WDR77 | |
| SCHEMBL13322633 | 0.79 | GRM5 (0.51) | DRD2DRD1DRD5DRD3HTR2A | |
| SCHEMBL13201488 | 0.78 | PRMT5 (0.50) | DRD2DRD1DRD3PRMT5WDR77 | |
| SCHEMBL20214501 | 0.77 | MEN1 (0.51) | DRD2DRD1DRD5DRD3HTR2A | |
| SCHEMBL4105407 | 0.77 | NOTUM (0.58) | DRD2DRD1DRD5DRD3HTR2C | |
| SCHEMBL12870758 | 0.77 | AOC3 (0.58) | DRD2DRD1DRD5DRD3HTR2A | |
| SCHEMBL13885025 | 0.76 | PDE3B (0.52) | DRD2DRD1DRD5DRD3NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE30456-E | ANTIFERTILITY AGENTS, ANTIINFLAMATORY AGENTS AND CENTRAL NERVOUS SYSTEM DEPRESSANTS | GRUPPO LEPETIT S.P.A. (IT) | 1980-12-23 | — | — | US | disclosed |
| US-4075341-A | 2-Substituted phenyl-5-triazols [5,1-a] isoquinoline compounds | GRUPPO LEPETIT S.P.A. (IT) | 1978-02-21 | — | — | US | disclosed |