Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.56 |
| ▸ | ITGAV | P06756 | 10/20 | 0.56 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.56 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.56 |
| ▸ | ITGB5 | P18084 | 6/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | MC4R | P32245 | 8/20 | 0.49 |
| ▸ | MC5R | P33032 | 8/20 | 0.49 |
| ▸ | MC3R | P41968 | 8/20 | 0.49 |
| ▸ | MC1R | Q01726 | 8/20 | 0.49 |
| ▸ | TSLP | Q969D9 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24253223 | 0.94 | ITGB3 (0.58) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL24253222 | 0.94 | ITGB3 (0.58) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL12528230 | 0.93 | ITGB3 (0.56) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL23823921 | 0.90 | ITGB3 (0.56) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL10138534 | 0.90 | ITGB3 (0.60) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL20822613 | 0.90 | ITGB3 (0.56) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL15397366 | 0.90 | ITGB3 (0.60) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL24253294 | 0.90 | ITGB3 (0.56) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL22970321 | 0.90 | ITGB3 (0.56) | ITGB3ITGAVITGB1ITGA5ITGB5 | |
| SCHEMBL7744260 | 0.90 | ITGB3 (0.56) | ITGB3ITGAVITGB1ITGA5ITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012095347-A9 | TRIAZACYCLONONANE-BASED PHOSPHINATE LIGAND AND ITS USE FOR MOLECULAR IMAGING | Technische Universität München (DE) | 2012-09-20 | — | — | WO | disclosed |
| WO-2012095347-A1 | TRIAZACYCLONONANE-BASED PHOSPHINATE LIGAND AND ITS USE FOR MOLECULAR IMAGING | Technische Universität München (DE) | 2012-07-19 | — | — | WO | disclosed |