Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.46 |
| ▸ | HRH1 | P35367 | 5/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6057465 | 0.90 | TSHR (0.42) | HTR2AHRH1ADRA2BSLC6A2SLC6A4 | |
| SCHEMBL11501576 | 0.86 | TAAR1 (0.50) | HTR2AHRH1TAAR1CHRM2ADRA2A | |
| SCHEMBL2417791 | 0.81 | TSHR (0.52) | TAAR1TDP1MAPK1HTTNPC1 | |
| SCHEMBL11425085 | 0.79 | CNR2 (0.44) | HTR2AHRH1TAAR1CHRM2ADRA2A | |
| SCHEMBL11411350 | 0.77 | EGFR (0.57) | HTR2AHRH1TAAR1TDP1CHRM2 | |
| SCHEMBL9773231 | 0.76 | KDM4E (0.46) | HTR2AHRH1TAAR1TDP1OPRK1 | |
| SCHEMBL8942276 | 0.76 | TSHR (0.55) | HTR2AHRH1TAAR1CHRM2ADRA2A | |
| SCHEMBL11456446 | 0.76 | EGFR (0.39) | HTR2AHRH1TDP1CHRM2ADRA2A | |
| SCHEMBL11749680 | 0.76 | TAAR1 (0.47) | HTR2AHRH1TAAR1CHRM2ADRA2A | |
| SCHEMBL17151053 | 0.76 | CNR2 (0.47) | HTR2AHRH1TAAR1TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4233214-A | FOR POLYACRYLONITRILE AND ACID-MODIFIED POLYESTERS OR POLYAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-11-11 | — | — | US | disclosed |
| US-4036826-A | Cationic azo dyestuffs with a hydroxyalkylated ammonium group | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-19 | — | — | US | disclosed |