Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.59 |
| ▸ | CA2 | P00918 | 4/20 | 0.59 |
| ▸ | MMP1 | P03956 | 1/20 | 0.59 |
| ▸ | MMP2 | P08253 | 1/20 | 0.59 |
| ▸ | MMP9 | P14780 | 1/20 | 0.59 |
| ▸ | MMP8 | P22894 | 1/20 | 0.59 |
| ▸ | MMP13 | P45452 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 3/20 | 0.57 |
| ▸ | CA9 | Q16790 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | IDO1 | P14902 | 3/20 | 0.55 |
| ▸ | F2 | P00734 | 1/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.55 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.55 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15798330 | 0.91 | CA1 (0.71) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL28550935 | 0.75 | CA1 (0.73) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL8224012 | 0.75 | CA1 (1.00) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL1102020 | 0.75 | CA1 (0.73) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL10992157 | 0.75 | CA1 (0.73) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL11408560 | 0.75 | F2 (0.61) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL11590063 | 0.74 | CA1 (0.67) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL2372596 | 0.74 | CA1 (0.71) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL6448306 | 0.74 | CA1 (0.56) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL6448310 | 0.74 | CA1 (0.56) | CA1CA2MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4218465-A | Glyoxylic acid hydrocarbylsulfonylhydrazones and therapeutic compositions | SRI INTERNATIONAL (US) | 1980-08-19 | — | — | US | disclosed |