Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.73 |
| ▸ | CA2 | P00918 | 2/20 | 0.73 |
| ▸ | MMP1 | P03956 | 1/20 | 0.73 |
| ▸ | MMP2 | P08253 | 1/20 | 0.73 |
| ▸ | MMP9 | P14780 | 1/20 | 0.73 |
| ▸ | MMP8 | P22894 | 1/20 | 0.73 |
| ▸ | MMP13 | P45452 | 1/20 | 0.73 |
| ▸ | POLB | P06746 | 2/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | DHFR | P00374 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | CA12 | O43570 | 1/20 | 0.65 |
| ▸ | CA9 | Q16790 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | IDO1 | P14902 | 2/20 | 0.61 |
| ▸ | F2 | P00734 | 1/20 | 0.61 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11590063 | 0.87 | CA1 (0.67) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL28550935 | 0.85 | CA1 (0.73) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL8224012 | 0.85 | CA1 (1.00) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL1102020 | 0.85 | CA1 (0.73) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL14609909 | 0.85 | SMN1; SMN2 (0.65) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL9887824 | 0.84 | SMN1; SMN2 (0.58) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL11602343 | 0.84 | CA1 (0.63) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL5187415 | 0.83 | CA12 (0.76) | CA1CA2SMN1; SMN2TSHRCA12 | |
| SCHEMBL14420813 | 0.83 | IDO1 (0.62) | CA1CA2POLBSMN1; SMN2DHFR | |
| SCHEMBL29277108 | 0.83 | TGM2 (0.67) | CA1CA2MMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9820997-B2 | Pharmaceutical composition for treating disease associated with demyelination of neurons and method of using the pharmaceutical composition | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2017-11-21 | — | — | US | disclosed |
| US-9820997-B2 | Pharmaceutical composition for treating disease associated with demyelination of neurons and method of using the pharmaceutical composition | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2017-11-21 | — | — | US | disclosed |
| CN-105884712-A | Compound capable of inhibiting activity of NEDD8 kinase as well as preparation method and pharmaceutical application of compound | 中国药科大学 | 2016-08-24 | — | — | CN | disclosed |
| US-20160120884-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING DISEASE ASSOCIATED WITH DEMYELINATION OF NEURONS AND METHOD OF USING THE PHARMACEUTICAL COMPOSITION | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2016-05-05 | — | — | US | disclosed |
| US-20160120884-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING DISEASE ASSOCIATED WITH DEMYELINATION OF NEURONS AND METHOD OF USING THE PHARMACEUTICAL COMPOSITION | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2016-05-05 | — | — | US | disclosed |
| US-20110197308-A1 | Plants Tolerant to HPPD Inhibitor Herbicides | BAYER CROPSCIENCE AG (DE) | 2011-08-11 | — | — | US | disclosed |
| US-4495365-A | N-Acylsulfonamide herbicidal antidotes | STAUFFER CHEMICAL CO. (US) | 1985-01-22 | — | — | US | disclosed |
| US-4347380-A | N-Acylsulfonamide herbicidal antidotes | STAUFFER CHEMICAL COMPANY (US) | 1982-08-31 | — | — | US | disclosed |
| US-4266078-A | N-Acylsulfonamide herbicidal antidotes | STAUFFER CHEMICAL COMPANY (US) | 1981-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160120884-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING DISEASE ASSOCIATED WITH DEMYELINATION OF NEURONS AND METHOD OF USING THE PHARMACEUTICAL COMPOSITION | PMP22, MAG, GAP43 | CA1 760/4885CA2 3044/4885MMP1 602/4885 |
| US-20110197308-A1 | Plants Tolerant to HPPD Inhibitor Herbicides | HPD, DDT, PGD | CA1 2381/4885CA2 1725/4885MMP1 2650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.