Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TYR | P14679 | 2/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | MIF | P14174 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11416885 | 0.98 | ALDH1A1 (0.57) | ALDH1A1ALOX15HSD17B10TDP1HPGD | |
| SCHEMBL1698927 | 0.89 | ALDH1A1 (0.45) | ALDH1A1ALOX15HSD17B10TDP1HPGD | |
| SCHEMBL29364103 | 0.85 | ALDH1A1 (0.67) | ALDH1A1ALOX15HSD17B10TDP1HPGD | |
| SCHEMBL109921 | 0.85 | ALDH1A1 (0.67) | ALDH1A1ALOX15HSD17B10TDP1HPGD | |
| SCHEMBL15941838 | 0.83 | ALDH1A1 (0.57) | ALDH1A1ALOX15HSD17B10TDP1HPGD | |
| Hydrochloric Acid SCHEMBL4359705 | 0.83 | ALDH1A1 (0.64) | ALDH1A1ALOX15HSD17B10TDP1HPGD | |
| SCHEMBL29851227 | 0.83 | ALDH1A1 (0.64) | ALDH1A1ALOX15HSD17B10TDP1HPGD | |
| SCHEMBL3859151 | 0.83 | ALDH1A1 (0.64) | ALDH1A1ALOX15HSD17B10TDP1HPGD | |
| SCHEMBL13412020 | 0.83 | ALDH1A1 (0.64) | ALDH1A1ALOX15HSD17B10TDP1HPGD | |
| SCHEMBL30621342 | 0.83 | ALDH1A1 (0.64) | ALDH1A1ALOX15HSD17B10TDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1980000561-A1 | ALPHA-ALKYL-O-OXY-BENZYLAMIN DERIVATIVES,PREPARATION THEREOF AND REMEDIES CONTAINING THEM | SANDOZ AG (CH) | 1980-04-03 | — | — | WO | disclosed |