Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 14/20 | 0.58 |
| ▸ | LPAR2 | Q9HBW0 | 11/20 | 0.58 |
| ▸ | LPAR1 | Q92633 | 8/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.39 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.39 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | CDC25A | P30304 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11422055 | 0.92 | — | — | |
| SCHEMBL16879780 | 0.86 | LPAR3 (0.69) | LPAR3LPAR2LPAR1 | |
| SCHEMBL5852225 | 0.85 | LPAR3 (0.58) | LPAR3LPAR2LPAR1CYP3A4LPAR6 | |
| SCHEMBL8044300 | 0.83 | LPAR3 (0.61) | LPAR3LPAR2LPAR1CYP3A4LPAR6 | |
| SCHEMBL5852206 | 0.83 | LPAR3 (0.61) | LPAR3LPAR2LPAR1CYP3A4LPAR6 | |
| SCHEMBL2150299 | 0.83 | LPAR3 (0.61) | LPAR3LPAR2LPAR1CYP3A4LPAR6 | |
| SCHEMBL11424957 | 0.81 | — | — | |
| SCHEMBL9500572 | 0.81 | LPAR3 (0.65) | LPAR3LPAR2LPAR1LPAR6LPAR4 | |
| SCHEMBL258312 | 0.79 | LPAR3 (0.62) | LPAR3LPAR2LPAR1CYP3A4LPAR6 | |
| SCHEMBL11861589 | 0.78 | LPAR3 (0.55) | LPAR3LPAR2LPAR1CYP3A4LPAR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4222930-A | VULCANIZABLE RUBBER, SILICEOUS FILLER | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1980-09-16 | — | — | US | disclosed |
| US-4152347-A | REINFORCING AGENTS IN VULCANIZABLE RUBBER MIXTURES WHICH CONTAIN A SILICA FILLER | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1979-05-01 | — | — | US | disclosed |