Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 15/20 | 0.61 |
| ▸ | LPAR2 | Q9HBW0 | 13/20 | 0.61 |
| ▸ | LPAR1 | Q92633 | 10/20 | 0.50 |
| ▸ | LPAR6 | P43657 | 5/20 | 0.42 |
| ▸ | LPAR4 | Q99677 | 5/20 | 0.42 |
| ▸ | LPAR5 | Q9H1C0 | 5/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2150299 | 1.00 | LPAR3 (0.61) | LPAR3LPAR2LPAR1LPAR6LPAR4 | |
| SCHEMBL8044300 | 1.00 | LPAR3 (0.61) | LPAR3LPAR2LPAR1LPAR6LPAR4 | |
| SCHEMBL5852225 | 0.98 | LPAR3 (0.58) | LPAR3LPAR2LPAR1LPAR6LPAR4 | |
| SCHEMBL2150345 | 0.90 | CYP3A4 (0.50) | LPAR3LPAR2LPAR1CYP3A4TSHR | |
| SCHEMBL1290340 | 0.88 | LPAR3 (0.69) | LPAR3LPAR2LPAR1 | |
| SCHEMBL11861589 | 0.85 | LPAR3 (0.55) | LPAR3LPAR2LPAR1LPAR6LPAR4 | |
| SCHEMBL8942445 | 0.84 | CYP3A4 (0.44) | LPAR3LPAR2LPAR1CYP3A4TSHR | |
| SCHEMBL11419239 | 0.83 | LPAR3 (0.58) | LPAR3LPAR2LPAR1LPAR6LPAR4 | |
| SCHEMBL258249 | 0.80 | LPAR3 (0.67) | LPAR3LPAR2LPAR1LPAR6LPAR4 | |
| SCHEMBL258188 | 0.80 | LPAR3 (0.67) | LPAR3LPAR2LPAR1LPAR6LPAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7153901-B2 | Low viscosity flame retardants are the reaction product of a mixed ester of tetrabromophthalic acid with diethylene glycol and propylene glycol with an acid anhydride, organic phosphate, or organic chlorophosphate; minimizing visible scorching of the flexible polyurethane foam during its production | ALBEMARLE CORPORATION (US) | 2006-12-26 | — | — | US | disclosed |
| EP-1685176-A2 | FLAME RETARDANT, ADDITIVE COMPOSITIONS, AND FLAME RETARDANT POLYURETHANES | ALBEMARLE CORPORATION (US) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005052018-A2 | FLAME RETARDANT, ADDITIVE COMPOSITIONS, AND FLAME RETARDANT POLYURETHANES | ALBEMARLE CORPORATION (US) | 2005-06-09 | — | — | WO | disclosed |
| US-20050113495-A1 | Flame retardant, additive compositions, and flame retardant polyurethanes | ALBEMARLE CORPORATION | 2005-05-26 | — | — | US | disclosed |