Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY11 | Q96G91 | 6/20 | 0.76 |
| ▸ | TIMP3 | P35625 | 5/20 | 0.76 |
| ▸ | HPSE | Q9Y251 | 5/20 | 0.76 |
| ▸ | RECQL | P46063 | 5/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.76 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.76 |
| ▸ | MAPT | P10636 | 4/20 | 0.76 |
| ▸ | PKM | P14618 | 4/20 | 0.76 |
| ▸ | MEN1 | O00255 | 3/20 | 0.76 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.76 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.76 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.76 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.76 |
| ▸ | USP2 | O75604 | 2/20 | 0.76 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.76 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.76 |
| ▸ | ENTPD3 | O75355 | 1/20 | 0.76 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.76 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11414391 | 0.97 | RECQL (0.80) | P2RY11TIMP3HPSERECQLKMT2A | |
| SCHEMBL11510571 | 0.91 | P2RY11 (0.83) | P2RY11TIMP3HPSERECQLKMT2A | |
| SCHEMBL11426011 | 0.90 | TIMP3 (0.77) | P2RY11TIMP3HPSERECQLKMT2A | |
| SCHEMBL11425759 | 0.89 | P2RY11 (0.63) | P2RY11TIMP3HPSERECQLKMT2A | |
| SCHEMBL11466093 | 0.89 | TIMP3 (0.67) | P2RY11TIMP3HPSERECQLKMT2A | |
| SCHEMBL11477425 | 0.88 | P2RY11 (0.79) | P2RY11TIMP3HPSERECQLKMT2A | |
| SCHEMBL11419759 | 0.87 | TIMP3 (0.57) | P2RY11TIMP3HPSERECQLKMT2A | |
| SCHEMBL16255254 | 0.87 | P2RY11 (0.84) | P2RY11TIMP3HPSERECQLKMT2A | |
| Suramin SCHEMBL30312075 | 0.86 | P2RY11 (1.00) | P2RY11TIMP3HPSERECQLKMT2A | |
| Suramin SCHEMBL29371906 | 0.86 | P2RY11 (1.00) | P2RY11TIMP3HPSERECQLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0008154-A1 | Ureylene phenylene anionic naphthalene-sulfonic acids, their use as complement system inhibitors in a body fluid and process for their preparation | AMERICAN CYANAMID COMPANY (US) | 1980-02-20 | — | — | EP | disclosed |
| US-4185033-A | COMPLEMENT INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1980-01-22 | — | — | US | disclosed |