Lavoltidine

Lavoltidine

SCHEMBL1142

Cn1nc(CO)nc1NCCCOc1cccc(CN2CCCCC2)c1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.55
TP53 P04637 1/20 0.55
CYP1A2 P05177 1/20 0.55
CYP3A4 P08684 1/20 0.55
CYP2D6 P10635 1/20 0.55
TSHR P16473 1/20 0.55
MAPK1 P28482 1/20 0.55
THPO P40225 1/20 0.55
MTOR P42345 1/20 0.55
RAB9A P51151 1/20 0.55
HIF1A Q16665 1/20 0.55
HRH2 P25021 2/20 0.54
HRH3 Q9Y5N1 1/20 0.52
MEN1 O00255 1/20 0.51
GMNN O75496 1/20 0.51
ALDH1A1 P00352 1/20 0.51
LMNA P02545 1/20 0.51
MAPT P10636 1/20 0.51
PMP22 Q01453 1/20 0.51
KMT2A Q03164 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11106320 1.00 SMN1; SMN2 (0.55) SMN1; SMN2TP53CYP1A2CYP3A4CYP2D6
SCHEMBL11010882 1.00 SMN1; SMN2 (0.55) SMN1; SMN2TP53CYP1A2CYP3A4CYP2D6
Lavoltidine SCHEMBL30095469 1.00 SMN1; SMN2 (0.55) SMN1; SMN2TP53CYP1A2CYP3A4CYP2D6
SCHEMBL10751306 0.97 SMN1; SMN2 (0.52) SMN1; SMN2TP53CYP1A2CYP3A4CYP2D6
Lavoltidine SCHEMBL633369 0.94 SMN1; SMN2 (0.52) SMN1; SMN2TP53CYP1A2CYP3A4CYP2D6
Acetic Acid SCHEMBL11011722 0.93 HRH2 (0.52) SMN1; SMN2TP53CYP1A2CYP3A4CYP2D6
SCHEMBL4607091 0.93 SMN1; SMN2 (0.54) SMN1; SMN2TP53CYP1A2CYP3A4CYP2D6
SCHEMBL11100251 0.92 TP53 (0.47) SMN1; SMN2TP53CYP1A2CYP3A4CYP2D6
SCHEMBL11068165 0.91 SMN1; SMN2 (0.52) SMN1; SMN2TP53CYP1A2CYP3A4CYP2D6
SCHEMBL11483567 0.91 TSHR (0.45) SMN1; SMN2TP53CYP1A2CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1050 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4704971-A1 GAMMA STIMULATION AND NEUROMODULATOR COMBINATION THERAPY Cognito Therapeutics, Inc. (US) 2026-03-11 EP claimed
WO-2024229174-A1 GAMMA STIMULATION AND NEUROMODULATOR COMBINATION THERAPY Cognito Therapeutics, Inc. (US) 2024-11-07 WO claimed
WO-2023219526-A1 MULTITARGET ANTIVIRAL DIETARY SUPPLEMENT PROKIN MILAN (RS) 2023-11-16 WO claimed
US-20230349922-A1 H2 Blockers Targeting Liver Macrophages for the Prevention and Treatment of Liver Disease and Cancer UNIVERSITÉ DE STRASBOURG (FR) 2023-11-02 US claimed
EP-4196793-A1 H2 BLOCKERS TARGETING LIVER MACROPHAGES FOR THE PREVENTION AND TREATMENT OF LIVER DISEASE AND CANCER Université de Strasbourg (FR) 2023-06-21 EP claimed
US-20230129326-A1 METHODS TO PREVENT SARS-COV-2 INFECTION AND TREAT COVID-19 NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2023-04-27 US claimed
EP-4132967-A2 METHODS TO PREVENT SARS-COV-2 INFECTION AND TREAT COVID-19 University of Florida Research Foundation, Incorporated (US) 2023-02-15 EP claimed
WO-2022034121-A1 H2 BLOCKERS TARGETING LIVER MACROPHAGES FOR THE PREVENTION AND TREATMENT OF LIVER DISEASE AND CANCER UNIVERSITÉ DE STRASBOURG (FR) 2022-02-17 WO claimed
US-20210353656-A1 COMBINATION OF NICOTINAMIDE MONONUCLEOTIDE DERIVATIVES AND HISTAMINE H2 RECEPTOR ANTAGONISTS FOR VIRAL INFECTIONS NUVAMID SA (CH) 2021-11-18 US claimed
WO-2020032883-A2 SYNERGISTIC EFFECTS OF A NOVEL KETOPROFEN FORMULATION INCLUDING A GASTRO PROTECTIVE AGENT PISAK MEHMET NEVZAT (TR) 2020-02-13 WO claimed
WO-1996016640-A1 ORAL COMPOSITIONS OF H2-ANTAGONISTS APPLIED ANALYTICAL INDUSTRIES, INC. (US) 1996-06-06 WO claimed
US-5364616-A Use of H-2 antagonists for treatment of gingivitis THE PROCTER & GAMBLE COMPANY (US) 1994-11-15 US claimed
US-5294433-A Dentistry THE PROCTER & GAMBLE COMPANY (US) 1994-03-15 US claimed
EP-0367484-B1 Carboxylic acid derivates GLAXO GROUP LTD (GB) 1994-02-16 EP claimed
WO-1993020815-A1 USE OF H-2 ANTAGONISTS FOR TREATMENT OF GINGIVITIS THE PROCTER & GAMBLE COMPANY (US) 1993-10-28 WO claimed
EP-0275669-B1 USE OF HETEROCYCLIC DERIVATIVES FOR THE MANUFACTURE OF MEDICAMENTS GLAXO GROUP LIMITED (GB) 1992-09-30 EP claimed
EP-0367484-A1 Carboxylic acid derivates GLAXO GROUP LIMITED (GB) 1990-05-09 EP claimed
EP-0275669-A1 Use of heterocyclic derivatives for the manufacture of medicaments GLAXO GROUP LIMITED (GB) 1988-07-27 EP claimed
EP-0016565-B1 1,2,4-TRIAZOLE DERIVATIVES, PROCESSES FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM GLAXO GROUP LIMITED (GB) 1984-05-23 EP claimed
EP-0016565-A1 1,2,4-Triazole derivatives, processes for their production and pharmaceutical compositions containing them GLAXO GROUP LIMITED (GB) 1980-10-01 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210353656-A1 COMBINATION OF NICOTINAMIDE MONONUCLEOTIDE DERIVATIVES AND HISTAMINE H2 RECEPTOR ANTAGONISTS FOR VIRAL INFECTIONS HRH2, HRH4, HRH3 SMN1; SMN2 3648/4885TP53 4137/4885CYP1A2 1909/4885
US-20230129326-A1 METHODS TO PREVENT SARS-COV-2 INFECTION AND TREAT COVID-19 ACE2, ACE, TMPRSS2 SMN1; SMN2 3431/4885TP53 1472/4885CYP1A2 1621/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.