Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28275679 | 1.00 | CA1 (0.61) | CA1TSHRALDH1A1CA4TDP1 | |
| Acetic Acid SCHEMBL6356170 | 1.00 | CA1 (0.61) | CA1TSHRALDH1A1CA4TDP1 | |
| Acetic Acid SCHEMBL297083 | 0.92 | CA1 (0.61) | CA1TSHRALDH1A1CA4TDP1 | |
| Acetic Acid SCHEMBL22217471 | 0.92 | CA1 (0.61) | CA1TSHRALDH1A1CA4TDP1 | |
| Acetic Acid SCHEMBL9796816 | 0.92 | — | — | |
| Acetic Acid SCHEMBL25381310 | 0.92 | CA1 (0.61) | CA1TSHRALDH1A1CA4TDP1 | |
| Acetic Acid SCHEMBL22217472 | 0.92 | — | — | |
| Acetic Acid SCHEMBL8414035 | 0.92 | — | — | |
| Acetic Acid SCHEMBL21489110 | 0.92 | CA1 (0.61) | CA1TSHRALDH1A1CA4TDP1 | |
| Acetic Acid SCHEMBL548946 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7884537-B2 | Pattern substrate including conductive pattern of overlapping circular patterns disposed on substrate | RICOH COMPANY, LTD. (JP) | 2011-02-08 | — | — | US | disclosed |
| US-20080138570-A1 | ELECTRON-EMITTING DEVICE AND IMAGE DISPLAY APPARATUS USING THE SAME | SEKIYA TAKURO | 2008-06-12 | — | — | US | disclosed |
| US-7355335-B2 | Electron-emitting device and image display apparatus using the same | RICOH COMPANY, LTD. (JP) | 2008-04-08 | — | — | US | disclosed |
| EP-0936652-B1 | Film formation method, method for fabricating electron emitting element employing the same film, and method for manufacturing image forming apparatus employing the same element | CANON KK (JP) | 2006-12-13 | — | — | EP | disclosed |
| US-20060028118-A1 | Electron-emitting device and image display apparatus using the same | SEKIYA TAKURO | 2006-02-09 | — | — | US | disclosed |
| US-6992433-B2 | Electron-emitting device and image display apparatus using the same | RICOH COMPANY, LTD. (JP) | 2006-01-31 | — | — | US | disclosed |
| US-20050202583-A1 | Antistatic film forming composition, and producing method for conductive film pattern, electron source and image display apparatus | CANON KABUSHIKI KAISHA (JP) | 2005-09-15 | — | — | US | disclosed |
| US-6815001-B1 | Electronic device, method for producing electron source and image forming device, and apparatus for producing electronic device | CANON KABUSHIKI KAISHA (JP) | 2004-11-09 | — | — | US | disclosed |
| US-6579139-B1 | Film formation method, method for fabricating electron emitting element employing the same film, and method for manufacturing image forming apparatus employing the same element | CANON KABUSHIKI KAISHA (JP) | 2003-06-17 | — | — | US | disclosed |
| US-20010024227-A1 | Electron-emitting device and image display apparatus using the same | RICOH COMPANY, LTD. | 2001-09-27 | — | — | US | disclosed |
| EP-0936652-A1 | Film formation method, method for fabricating electron emitting element employing the same film, and method for manufacturing image forming apparatus employing the same element | CANON KABUSHIKI KAISHA (JP) | 1999-08-18 | — | — | EP | disclosed |