Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL5572126 | 1.00 | CA1 (0.61) | CA1TSHRALDH1A1CA4TDP1 | |
| Acetic Acid SCHEMBL28637775 | 0.96 | CA1 (0.57) | CA1TSHRALDH1A1CA4TDP1 | |
| Acetic Acid SCHEMBL6356170 | 0.92 | CA1 (0.61) | CA1TSHRALDH1A1CA4TDP1 | |
| Acetic Acid SCHEMBL9796816 | 0.92 | — | — | |
| Acetic Acid SCHEMBL1142260 | 0.92 | CA1 (0.61) | CA1TSHRALDH1A1CA4TDP1 | |
| Acetic Acid SCHEMBL25381310 | 0.92 | CA1 (0.61) | CA1TSHRALDH1A1CA4TDP1 | |
| Acetic Acid SCHEMBL22217471 | 0.92 | CA1 (0.61) | CA1TSHRALDH1A1CA4TDP1 | |
| Acetic Acid SCHEMBL8414035 | 0.92 | — | — | |
| Acetic Acid SCHEMBL22217472 | 0.92 | — | — | |
| Acetic Acid SCHEMBL21489110 | 0.92 | CA1 (0.61) | CA1TSHRALDH1A1CA4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114481606-B | Nickel-containing carbon nano tube/copper composite fiber and preparation method thereof | 中国科学院苏州纳米技术与纳米仿生研究所 | 2023-06-02 | — | — | CN | claimed |
| CN-113540403-B | High-stability three-dimensional porous lithium metal anode and preparation method and application thereof | 中南大学 | 2023-04-28 | — | — | CN | claimed |
| CN-111250038-B | Method for separating and purifying hexafluoropropylene dimer and adsorbent used by same | 临海市利民化工有限公司（CN） | 2023-01-13 | — | — | CN | claimed |
| CN-114815429-A | Nickel oxide nano hierarchical structure electrochromic capacitor material and preparation method thereof | 合肥工业大学 | 2022-07-29 | — | — | CN | claimed |
| CN-114481606-A | Nickel-containing carbon nanotube/copper composite fiber and preparation method thereof | 中国科学院苏州纳米技术与纳米仿生研究所 | 2022-05-13 | — | — | CN | claimed |
| CN-111250038-A | Method for separating and purifying hexafluoropropylene dimer and adsorbent used by same | 临海市利民化工有限公司 | 2020-06-09 | — | — | CN | claimed |
| CN-109200965-A | It is a kind of for synthesizing nickel oxide nanoparticle/porous carbon composite material ultrasonic wave microreactor system and application method | 金陵科技学院 | 2019-01-15 | — | — | CN | claimed |
| CN-105543920-B | Magnesium alloy differential arc oxidation layer surface prepares the processing method of conductive coating | 嘉瑞科技（惠州）有限公司 | 2017-11-28 | — | — | CN | claimed |
| CN-116078434-B | Cobalt-nitrogen coordination modified covalent triazine framework material PCTF-Co and preparation method and application thereof | 浙江工业大学 | 2024-07-02 | — | — | CN | disclosed |
| CN-116651514-B | Photocatalytic composite film and preparation method thereof | 南京信息工程大学 | 2024-05-31 | — | — | CN | disclosed |
| CN-117832517-A | Zinc-bromine flow battery negative electrode material, preparation method thereof and zinc-bromine flow battery | 郑州中科新兴产业技术研究院 | 2024-04-05 | — | — | CN | disclosed |
| CN-116651514-A | Photocatalytic composite film and preparation method thereof | 南京信息工程大学 | 2023-08-29 | — | — | CN | disclosed |
| CN-114481606-B | Nickel-containing carbon nano tube/copper composite fiber and preparation method thereof | 中国科学院苏州纳米技术与纳米仿生研究所 | 2023-06-02 | — | — | CN | disclosed |
| CN-116078434-A | Cobalt-nitrogen coordination modified covalent triazine framework material PCTF-Co, and preparation method and application thereof | 浙江工业大学 | 2023-05-09 | — | — | CN | disclosed |
| EP-0997868-A1 | Field sequential liquid crystal display device and driving method thereof, and head mounted display | SEL SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2000-05-03 | — | — | EP | disclosed |
| CN-1205247-A | Non-crystalline catalyst containing Ni and P it prepn. method and application | CHINA PETROCHEMICAL CORP (CN) | 1999-01-20 | — | — | CN | disclosed |
| CN-1200955-A | Catalyst containing Ni-P non-crystalline-state alloy, preparation method and application thereof | CHINA PETROCHEMICAL CORP (CN) | 1998-12-09 | — | — | CN | disclosed |
| CN-1196975-A | Non-crystalline alloy catalyst containing Ni and B, its prepn. and application | CHINA PETROCHEMICAL CORP (CN) | 1998-10-28 | — | — | CN | disclosed |
| CN-1179358-A | Ni-B amorphous alloy catalyst, its preparing process and application | CHINA PETROCHEMICAL CORP (CN) | 1998-04-22 | — | — | CN | disclosed |
| EP-0389158-A1 | High activity nickel catalyst and process for preparation thereof | UBE INDUSTRIES, LTD. (JP) | 1990-09-26 | — | — | EP | disclosed |