Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | VDR | P11473 | 1/20 | 0.30 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.30 |
| ▸ | CDC25A | P30304 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11422599 | 1.00 | TSHR (0.41) | TSHRHSD17B10CYP3A4SMN1; SMN2EPHX2 | |
| SCHEMBL11427404 | 0.89 | EPHX2 (0.40) | TSHRHSD17B10EPHX2MAPTALDH1A1 | |
| SCHEMBL11427402 | 0.89 | EPHX2 (0.40) | TSHRHSD17B10EPHX2MAPTALDH1A1 | |
| SCHEMBL11425966 | 0.88 | MAPT (0.39) | MAPTALDH1A1VDRGPBAR1CDC25A | |
| SCHEMBL11435968 | 0.88 | MAPT (0.39) | MAPTALDH1A1VDRGPBAR1CDC25A | |
| SCHEMBL11429285 | 0.88 | MAPT (0.39) | MAPTALDH1A1VDRGPBAR1CDC25A | |
| SCHEMBL11425952 | 0.81 | MAPT (0.43) | MAPTCDC25A | |
| SCHEMBL11430684 | 0.81 | MAPT (0.43) | MAPTCDC25A | |
| SCHEMBL11425948 | 0.81 | MAPT (0.43) | MAPTCDC25A | |
| SCHEMBL11430483 | 0.80 | MAPT (0.42) | EPHX2MAPTHRH3CDC25A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4228304-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, ANTIULCER AGENTS, BACTERICIDES, ANTITHROMBOTIC AGENTS AND FOR LIVER DISORDERS, OR AS SURFACTANTS IN DETERGENTS AND OIL ADDITIVES | HISAMITSU PHARMACEUTICAL CO. INC. (JP) | 1980-10-14 | — | — | US | disclosed |