Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CDC25A | P30304 | 3/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 5/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.33 |
| ▸ | BMP1 | P13497 | 1/20 | 0.33 |
| ▸ | VDR | P11473 | 1/20 | 0.33 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
| ▸ | CDC25B | P30305 | 1/20 | 0.31 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.31 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11435968 | 1.00 | MAPT (0.39) | MAPTCDC25AMMEGPBAR1NR1H4 | |
| SCHEMBL11425966 | 1.00 | MAPT (0.39) | MAPTCDC25AMMEGPBAR1NR1H4 | |
| SCHEMBL11422602 | 0.88 | TSHR (0.41) | MAPTCDC25AGPBAR1VDRALDH1A1 | |
| SCHEMBL11422599 | 0.88 | TSHR (0.41) | MAPTCDC25AGPBAR1VDRALDH1A1 | |
| SCHEMBL11430684 | 0.87 | MAPT (0.43) | MAPTCDC25AEPHA2LMNAFNTA | |
| SCHEMBL11425952 | 0.87 | MAPT (0.43) | MAPTCDC25AEPHA2LMNAFNTA | |
| SCHEMBL11425948 | 0.87 | MAPT (0.43) | MAPTCDC25AEPHA2LMNAFNTA | |
| SCHEMBL11430483 | 0.86 | MAPT (0.42) | MAPTCDC25ALMNAFNTAFNTB | |
| SCHEMBL11427404 | 0.85 | EPHX2 (0.40) | MAPTNR1H4BMP1ALDH1A1FNTA | |
| SCHEMBL11427402 | 0.85 | EPHX2 (0.40) | MAPTNR1H4BMP1ALDH1A1FNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4228304-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, ANTIULCER AGENTS, BACTERICIDES, ANTITHROMBOTIC AGENTS AND FOR LIVER DISORDERS, OR AS SURFACTANTS IN DETERGENTS AND OIL ADDITIVES | HISAMITSU PHARMACEUTICAL CO. INC. (JP) | 1980-10-14 | — | — | US | disclosed |