Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD40 | P25942 | 3/20 | 0.62 |
| ▸ | CD40LG | P29965 | 3/20 | 0.62 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.57 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.57 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.57 |
| ▸ | CASP6 | P55212 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.50 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11428711 | 0.95 | CD40 (0.66) | CD40CD40LGDUSP3PTPN5PTPN11 | |
| SCHEMBL11432355 | 0.92 | CD40 (0.63) | CD40CD40LGDUSP3PTPN5PTPN11 | |
| SCHEMBL11430290 | 0.89 | KMT2A (0.63) | CD40CD40LGDUSP3PTPN5PTPN11 | |
| SCHEMBL11431112 | 0.88 | CD40 (0.61) | CD40CD40LGDUSP3PTPN5PTPN11 | |
| SCHEMBL11425283 | 0.88 | CD40 (0.64) | CD40CD40LGDUSP3PTPN5PTPN11 | |
| SCHEMBL11421827 | 0.88 | CD40 (0.63) | CD40CD40LGDUSP3PTPN5PTPN11 | |
| SCHEMBL11757962 | 0.86 | CD40 (0.66) | CD40CD40LGDUSP3PTPN5PTPN11 | |
| SCHEMBL11426141 | 0.84 | KMT2A (0.63) | CD40CD40LGDUSP3PTPN5PTPN11 | |
| SCHEMBL11423070 | 0.84 | CD40 (0.66) | CD40CD40LGDUSP3PTPN5PTPN11 | |
| SCHEMBL11425089 | 0.83 | CD40 (0.72) | CD40CD40LGDUSP3PTPN5PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216166-A | Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |