SCHEMBL11423328

SCHEMBL11423328

Oc1ccc2ccccc2c1/N=N/c1nccc2ccccc12

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.66
L3MBTL1 Q9Y468 5/20 0.66
TDP1 Q9NUW8 5/20 0.66
KDM4E B2RXH2 4/20 0.66
HSP90AA1 P07900 3/20 0.66
LMNA P02545 3/20 0.66
POLB P06746 2/20 0.66
NPSR1 Q6W5P4 2/20 0.66
NPC1 O15118 2/20 0.66
SMN1; SMN2 Q16637 2/20 0.66
ALDH1A1 P00352 2/20 0.66
HPGD P15428 1/20 0.66
ALOX12 P18054 1/20 0.66
OPRK1 P41145 1/20 0.66
HTT P42858 1/20 0.66
KMT2A Q03164 5/20 0.59
MEN1 O00255 4/20 0.59
MAPK1 P28482 4/20 0.59
THRB P10828 4/20 0.59
KCNH2 Q12809 3/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11423332 1.00 MAPT (0.66) MAPTL3MBTL1TDP1KDM4EHSP90AA1
SCHEMBL2927757 0.83 THRB (0.81) MAPTL3MBTL1TDP1KDM4EHSP90AA1
SCHEMBL11621517 0.83 THRB (0.81) MAPTL3MBTL1TDP1KDM4EHSP90AA1
SCHEMBL27998930 0.83 PLAU (0.63) MAPTL3MBTL1TDP1KDM4EHSP90AA1
SCHEMBL30702583 0.83 THRB (0.81) MAPTL3MBTL1TDP1KDM4EHSP90AA1
SCHEMBL7221216 0.82 MAPT (0.63) MAPTL3MBTL1TDP1KDM4EHSP90AA1
SCHEMBL7221215 0.82 MAPT (0.63) MAPTL3MBTL1TDP1KDM4EHSP90AA1
SCHEMBL31319486 0.79 MAPT (1.00) MAPTL3MBTL1TDP1KDM4EHSP90AA1
SCHEMBL29354223 0.79 MAPT (1.00) MAPTL3MBTL1TDP1KDM4EHSP90AA1
SCHEMBL272188 0.79 MAPT (1.00) MAPTL3MBTL1TDP1KDM4EHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4201588-A NONSILVER PHOTOGRAPHIC FILMS; DISULFIDE, DIAZOANTHRONE, DIAZOPHENANTHRONE, AROMATIC AZIDE, CARBAZIDES OR QUINONES AS PHOTOREDUCTANT; EXTERNAL HYDROGEN SOURCE EASTMAN KODAK COMPANY (US) 1980-05-06 US disclosed
US-4171221-A NONSILVER PHOTOGTAPHY EASTMAN KODAK COMPANY (US) 1979-10-16 US disclosed
US-4131463-A Electric recording process of images using electron sensitive layer containing trivalent cobalt complex and compound having conjugated π bond system FUJI PHOTO FILM CO., LTD. (JP) 1978-12-26 US disclosed