Uric Acid

Uric Acid

SCHEMBL11423974

O=c1[nH]c(=O)c2[nH]c(=O)[nH]c2[nH]1.[NaH].[NaH]

nearest known ligand 0.94

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GDA Q9Y2T3 2/20 0.94
ALDH1A1 P00352 4/20 0.46
CYP1A2 P05177 2/20 0.46
CYP2C9 P11712 2/20 0.46
HPGD P15428 2/20 0.46
CYP2C19 P33261 2/20 0.46
HSD17B10 Q99714 2/20 0.46
ALOX15 P16050 1/20 0.46
MAPT P10636 3/20 0.46
KDM4E B2RXH2 2/20 0.46
GAA P10253 1/20 0.46
PKM P14618 1/20 0.46
BRPF1 P55201 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
TYMP P19971 5/20 0.39
GSK3B P49841 1/20 0.39
BACE1 P56817 1/20 0.39
IDH1 O75874 1/20 0.39
CSNK2A2 P19784 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Uric Acid SCHEMBL229866 1.00 GDA (0.94) GDAALDH1A1CYP1A2CYP2C9HPGD
Uric Acid SCHEMBL924097 0.97 GDA (0.89) GDAALDH1A1CYP1A2CYP2C9HPGD
Uric Acid SCHEMBL3417988 0.97 GDA (1.00) GDAALDH1A1CYP1A2CYP2C9HPGD
Uric Acid SCHEMBL22069923 0.97 GDA (1.00) GDAALDH1A1CYP1A2CYP2C9HPGD
Uric Acid SCHEMBL7933 0.97 GDA (1.00) GDAALDH1A1CYP1A2CYP2C9HPGD
Uric Acid SCHEMBL1331321 0.97 GDA (1.00) GDAALDH1A1CYP1A2CYP2C9HPGD
Uric Acid SCHEMBL11473111 0.95 GDA (0.84) GDAALDH1A1CYP1A2CYP2C9HPGD
Uric Acid SCHEMBL2434620 0.94 GDA (0.94) GDAALDH1A1CYP1A2CYP2C9HPGD
Uric Acid SCHEMBL16213309 0.94 GDA (0.94) GDAALDH1A1CYP1A2CYP2C9HPGD
Uric Acid SCHEMBL196769 0.94 GDA (0.94) GDAALDH1A1CYP1A2CYP2C9HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108752350-A A kind of synthetic method of two piperidines of bis- (the diethanol amine) -4,8- of 2,6--pyrimidine-[5,4-d] and pyrimidine 锁浩 2018-11-06 CN claimed
CN-122081446-A Quality control liquid, kit and application thereof in combined detection of glucose and uric acid 2026-05-26 CN disclosed
US-20240369543-A1 MEASURING REAGENT FOR CROSS-LINKED N-TELOPEPTIDE OF TYPE I COLLAGEN, PREPARATION METHOD THEREOF, AND IMMUNOASSAY METHOD USING SAME SEKISUI MEDICAL CO., LTD. (JP) 2024-11-07 US disclosed
WO-2023068249-A1 MEASURING REAGENT FOR CROSS-LINKED N-TELOPEPTIDE OF TYPE I COLLAGEN, PREPARATION METHOD THEREOF, AND IMMUNOASSAY METHOD USING SAME 積水メディカル株式会社 2023-04-27 WO disclosed
CN-108752350-A A kind of synthetic method of two piperidines of bis- (the diethanol amine) -4,8- of 2,6--pyrimidine-[5,4-d] and pyrimidine 锁浩 2018-11-06 CN disclosed
CN-106215046-A A kind of Chinese medicine treating acute gouty arthritis 周子朋 2016-12-14 CN disclosed
US-4196290-A KILLING MICROORGANISMS THE GATES RUBBER COMPANY (US) 1980-04-01 US disclosed
US-4045582-A FEED SUPPLEMENT THE GATES RUBBER COMPANY (US) 1977-08-30 US disclosed