SCHEMBL11425

SCHEMBL11425

Nc1ccc(F)cc1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29595875 1.00
Fluoride SCHEMBL29165726 0.97 ALDH1A1 (0.94)
Methane SCHEMBL22289605 0.97 ALDH1A1 (0.94)
Hydrochloric Acid SCHEMBL7125109 0.97 ALDH1A1 (0.94)
Hydrochloric Acid SCHEMBL3851075 0.97 ALDH1A1 (0.94)
Cyanide SCHEMBL27761725 0.92 ALDH1A1 (0.85)
SCHEMBL3982613 0.90 ALDH1A1 (0.81)
Sulfuric Acid SCHEMBL34463729 0.86 ALDH1A1 (0.74)
Formic Acid SCHEMBL28834640 0.86 ALDH1A1 (0.74)
Sulfuric Acid SCHEMBL6705350 0.86 ALDH1A1 (0.74)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4224 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119798252-A Method for preparing N-ortho-acyl substituted nitrogen-containing heterocyclic compound and amine-shrinking iron (II) complex thereof 中国石油化工股份有限公司 2025-04-11 CN claimed
CN-119707801-A Preparation method for obtaining nicotinamide through emulsion layer of nicotinoyl reaction product 江苏颖盛化工有限公司 2025-03-28 CN claimed
CN-119731213-A Modified styrene elastomer 株式会社力森诺科 2025-03-28 CN claimed
CN-119684813-A Azo dichroism dye and preparation method and application thereof 苏州苏凯路化学科技有限公司 2025-03-25 CN claimed
CN-115784832-B Method for preparing 1,2, 4-trifluoro-benzene by cracking diazonium fluoborate 荣成青木高新材料有限公司 2025-03-07 CN claimed
CN-119552183-A Narrow emission compound based on spirobifluorene and electroluminescent device prepared from narrow emission compound 中国科学院宁波材料技术与工程研究所 2025-03-04 CN claimed
CN-119504340-A Preparation method of multi-fluorine substituted benzene series compounds based on diazonium salt 云南云天化股份有限公司 2025-02-25 CN claimed
CN-222305715-U Tubular hydrogenation device for preparing 2, 4-difluoroaniline 浙江解氏新材料股份有限公司 2025-01-07 CN claimed
CN-119143751-A N-ortho-acyl substituted nitrogen-containing heterocyclic compound and preparation method of amine-shrinking iron (II) complex thereof 中国石油化工股份有限公司 2024-12-17 CN claimed
CN-119143750-A Preparation method of N-ortho-alkyl substituted 1, 10-phenanthroline compound and catalyst prepared by same 中国石油化工股份有限公司 2024-12-17 CN claimed
EP-0322643-B1 MEDICINES CONTAINING AS A MIXTURE INTERFERON AND 1-DESOXY-PIPERIDINOSES, PROCESS FOR THEIR MANUFACTURE AND THEIR USE BAYER AG (DE) 1991-07-24 EP claimed
US-4939290-A Bactericides PFIZER INC. (US) 1990-07-03 US claimed
US-4935413-A ELASTICITY, ADHESION AND DISPERSIBILITY NIPPON PAINT CO., LTD. (JP) 1990-06-19 US claimed
EP-0370686-A2 A process for preparing quinolone carboxylic acid intermediates PFIZER INC. (US) 1990-05-30 EP claimed
EP-0001825-B1 METHOD OF PREPARING 2,4-DIFLUOROANILINE MERCK & CO. INC. (US) 1982-01-13 EP claimed
US-4294988-A Method of preparing 2,4-difluoroaniline MERCK & CO., INC. (US) 1981-10-13 US claimed
US-4225730-A Process for preparing 4-(2,4-difluorophenyl)-salicyclic acid MERCK & CO., INC. (US) 1980-09-30 US claimed
EP-0001825-A1 Method of preparing 2,4-difluoroaniline MERCK & CO. INC. (US) 1979-05-16 EP claimed
US-4145364-A PREPARATION OF FLUORINATED ANILINES MERCK & CO., INC. (US) 1979-03-20 US claimed
US-4140719-A Solid-liquid phase transfer catalysis improved method of preparing 2,4-difluoroaniline MERCK & CO., INC. (US) 1979-02-20 US claimed