Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 4/20 | 0.71 |
| ▸ | AR | P10275 | 2/20 | 0.71 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.71 |
| ▸ | NR3C2 | P08235 | 7/20 | 0.67 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 8/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11422308 | 0.97 | PGR (0.71) | PGRARCHRM1NR3C2NR3C1 | |
| SCHEMBL11442151 | 0.97 | PGR (0.73) | PGRARCHRM1NR3C2NR3C1 | |
| SCHEMBL11293588 | 0.96 | PGR (0.70) | PGRARCHRM1NR3C2NR3C1 | |
| SCHEMBL11436826 | 0.95 | PGR (0.71) | PGRARCHRM1NR3C2NR3C1 | |
| SCHEMBL11421124 | 0.95 | PGR (0.71) | PGRARCHRM1NR3C2NR3C1 | |
| SCHEMBL11433137 | 0.95 | PGR (0.68) | PGRARCHRM1NR3C2NR3C1 | |
| SCHEMBL11423697 | 0.95 | PGR (0.70) | PGRARCHRM1NR3C2NR3C1 | |
| SCHEMBL11431092 | 0.94 | PGR (0.74) | PGRARCHRM1NR3C2NR3C1 | |
| SCHEMBL11428424 | 0.94 | PGR (0.68) | PGRARCHRM1NR3C2NR3C1 | |
| SCHEMBL11424211 | 0.94 | PGR (0.81) | PGRARCHRM1NR3C2NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4242334-A | ANTIINFLAMMATORY AGENTS; SKIN DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-12-30 | — | — | US | disclosed |