Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.48 |
| ▸ | RELA | Q04206 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11418346 | 0.82 | SMN1; SMN2 (0.56) | SMN1; SMN2NPC1TP53RAB9APOLB | |
| SCHEMBL11415064 | 0.80 | SMN1; SMN2 (0.75) | SMN1; SMN2NPC1TP53RAB9APOLB | |
| SCHEMBL11246006 | 0.79 | RAB9A (0.49) | SMN1; SMN2NPC1TP53RAB9APOLB | |
| SCHEMBL11408778 | 0.79 | NR1H2 (0.50) | SMN1; SMN2NPC1TP53RAB9APOLB | |
| SCHEMBL11421901 | 0.79 | NPC1 (0.58) | SMN1; SMN2NPC1TP53RAB9APOLB | |
| SCHEMBL11415109 | 0.77 | NPC1 (0.53) | SMN1; SMN2NPC1TP53RAB9APOLB | |
| SCHEMBL11420919 | 0.76 | RAB9A (0.44) | SMN1; SMN2NPC1TP53RAB9APOLB | |
| SCHEMBL11240902 | 0.76 | NPC1 (0.59) | SMN1; SMN2NPC1TP53RAB9APOLB | |
| SCHEMBL11414643 | 0.74 | NPY5R (0.44) | SMN1; SMN2NPC1TP53RAB9APOLB | |
| SCHEMBL11408809 | 0.74 | NPC1 (0.57) | SMN1; SMN2NPC1TP53RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE30456-E | ANTIFERTILITY AGENTS, ANTIINFLAMATORY AGENTS AND CENTRAL NERVOUS SYSTEM DEPRESSANTS | GRUPPO LEPETIT S.P.A. (IT) | 1980-12-23 | — | — | US | disclosed |