Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | RORB | Q92753 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11433951 | 0.91 | BRD9 (0.46) | KCNA3BRD9KDM4EHSD17B10ALOX15 | |
| SCHEMBL11428824 | 0.88 | KCNA3 (0.41) | KCNA3BRD9KDM4EHSD17B10MAPK14 | |
| SCHEMBL11175526 | 0.87 | PTPN5 (0.46) | KCNA3BRD9KDM4EHSD17B10ALOX15 | |
| Fluridone SCHEMBL54579 | 0.87 | BRD9 (0.43) | BRD9ALOX15ALOX12SCN9AAKR1C3 | |
| Fluridone SCHEMBL6751451 | 0.87 | BRD9 (0.43) | BRD9ALOX15ALOX12SCN9AAKR1C3 | |
| SCHEMBL11434886 | 0.87 | MAOB (0.41) | KCNA3BRD9KDM4EHSD17B10MAPK14 | |
| SCHEMBL11434477 | 0.86 | MAPT (0.45) | KCNA3BRD9KDM4EHSD17B10MAPK14 | |
| SCHEMBL11429488 | 0.86 | ALOX15 (0.42) | KCNA3BRD9KCNH2KDM4EHSD17B10 | |
| SCHEMBL11426704 | 0.86 | BRD9 (0.43) | BRD9KDM4EHSD17B10MAPK14ALOX15 | |
| SCHEMBL11547968 | 0.84 | BRD9 (0.42) | KCNA3BRD9KDM4EHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152136-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1979-05-01 | — | — | US | claimed |
| US-4235619-A | USING 3-PHENYL-4(1H)-PYRIDONES OR PYRIDINETHIONES | ELI LILLY AND COMPANY (US) | 1980-11-25 | — | — | US | disclosed |
| US-4152136-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1979-05-01 | — | — | US | disclosed |