Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TIMP3 | P35625 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11427817 | 0.90 | HSD17B10 (0.50) | HSD17B10HDAC1SMN1; SMN2NPSR1MEN1 | |
| SCHEMBL11440731 | 0.89 | HSD17B10 (0.49) | HSD17B10HDAC1SMN1; SMN2NPSR1MEN1 | |
| SCHEMBL11433031 | 0.88 | HDAC1 (0.48) | HSD17B10HDAC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11782093 | 0.85 | HSD17B10 (0.56) | HSD17B10HDAC1SMN1; SMN2NPSR1MEN1 | |
| SCHEMBL10909467 | 0.84 | KMT2A (0.50) | HSD17B10MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL11349457 | 0.84 | KMT2A (0.58) | HSD17B10MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL11436219 | 0.84 | HSD17B10 (0.52) | HSD17B10HDAC1SMN1; SMN2NPSR1MEN1 | |
| SCHEMBL11431004 | 0.83 | HDAC1 (0.53) | HSD17B10HDAC1SMN1; SMN2NPSR1MEN1 | |
| SCHEMBL11428112 | 0.82 | MEN1 (0.41) | HSD17B10HDAC1MEN1KMT2AMAPT | |
| SCHEMBL11425883 | 0.82 | MEN1 (0.41) | HSD17B10HDAC1SMN1; SMN2NPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216165-A | Amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |