Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.41 |
| ▸ | ULK1 | O75385 | 1/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11428577 | 0.88 | HDAC1 (0.51) | HDAC1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL11440904 | 0.84 | HSD17B10 (0.52) | HDAC1SMN1; SMN2NPSR1HSD17B10MEN1 | |
| SCHEMBL11350051 | 0.84 | KMT2A (0.53) | HSD17B10MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL10907651 | 0.84 | NPC1 (0.45) | HSD17B10MEN1KMT2AALDH1A1APEX1 | |
| SCHEMBL11426573 | 0.83 | HSD17B10 (0.50) | HDAC1SMN1; SMN2NPSR1HSD17B10MEN1 | |
| SCHEMBL11440740 | 0.82 | MEN1 (0.41) | HDAC1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL11428049 | 0.82 | MEN1 (0.41) | HDAC1MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL11433446 | 0.81 | NPC1 (0.60) | SMN1; SMN2NPSR1MEN1KMT2AMAPT | |
| SCHEMBL11829001 | 0.81 | SMN1; SMN2 (0.53) | HDAC1SMN1; SMN2NPSR1HSD17B10MEN1 | |
| SCHEMBL11782093 | 0.80 | HSD17B10 (0.56) | HDAC1SMN1; SMN2NPSR1HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216165-A | Amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |