Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIMP3 | P35625 | 5/20 | 0.60 |
| ▸ | RECQL | P46063 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 2/20 | 0.58 |
| ▸ | HPSE | Q9Y251 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | P2RY11 | Q96G91 | 4/20 | 0.53 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.53 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 3/20 | 0.53 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.53 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.53 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.53 |
| ▸ | ENTPD3 | O75355 | 1/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11430062 | 0.99 | TIMP3 (0.59) | TIMP3RECQLKMT2AHSD17B10TDP1 | |
| SCHEMBL11593603 | 0.92 | TIMP3 (0.68) | TIMP3RECQLKMT2AHSD17B10TDP1 | |
| SCHEMBL11425899 | 0.86 | TIMP3 (0.56) | TIMP3RECQLKMT2AHSD17B10TDP1 | |
| SCHEMBL11406508 | 0.86 | P2RY11 (0.72) | TIMP3RECQLKMT2AHSD17B10TDP1 | |
| SCHEMBL11407259 | 0.85 | TIMP3 (0.55) | TIMP3RECQLKMT2AHSD17B10TDP1 | |
| SCHEMBL11425989 | 0.84 | TIMP3 (0.64) | TIMP3RECQLKMT2AHSD17B10TDP1 | |
| SCHEMBL11432619 | 0.84 | APEX1 (0.46) | TIMP3RECQLKMT2AHSD17B10TDP1 | |
| SCHEMBL11425858 | 0.83 | TIMP3 (0.62) | TIMP3RECQLKMT2AHSD17B10TDP1 | |
| SCHEMBL3300014 | 0.83 | HSD17B10 (0.74) | TIMP3RECQLKMT2AHSD17B10TDP1 | |
| SCHEMBL11466093 | 0.82 | TIMP3 (0.67) | TIMP3RECQLKMT2AHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0008154-A1 | Ureylene phenylene anionic naphthalene-sulfonic acids, their use as complement system inhibitors in a body fluid and process for their preparation | AMERICAN CYANAMID COMPANY (US) | 1980-02-20 | — | — | EP | disclosed |
| US-4185033-A | COMPLEMENT INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1980-01-22 | — | — | US | disclosed |
| US-4185032-A | COMPLEMENT INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1980-01-22 | — | — | US | disclosed |