Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | GLS | O94925 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10952699 | 0.84 | POLB (0.53) | POLBALDH1A1GLSGAAATM | |
| SCHEMBL14977352 | 0.82 | POLB (0.52) | POLBALDH1A1GLSGAAATM | |
| SCHEMBL11259355 | 0.82 | POLB (0.54) | POLBALDH1A1GLSGAAATM | |
| SCHEMBL10130895 | 0.78 | HPGD (0.53) | POLBALDH1A1GLSGAAF2 | |
| SCHEMBL22861048 | 0.77 | POLB (0.37) | POLBALDH1A1GLS | |
| SCHEMBL7161882 | 0.76 | — | — | |
| SCHEMBL14977428 | 0.75 | ALDH1A1 (0.86) | POLBALDH1A1GLSGAAATM | |
| SCHEMBL14975757 | 0.75 | ALDH1A1 (0.95) | POLBALDH1A1GLSGAAATM | |
| SCHEMBL27612227 | 0.75 | POLB (0.52) | POLBALDH1A1GLSGAAATM | |
| SCHEMBL1968819 | 0.74 | ALDH1A1 (0.88) | POLBALDH1A1GLSGAAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023067515-A1 | THIADIAZOLYL COMPOUNDS AS DNA POLYMERASE THETA INHIBITORS | IDEAYA BIOSCIENCES, INC. (US) | 2023-04-27 | — | — | WO | disclosed |
| WO-2023067515-A1 | THIADIAZOLYL COMPOUNDS AS DNA POLYMERASE THETA INHIBITORS | IDEAYA BIOSCIENCES, INC. (US) | 2023-04-27 | — | — | WO | disclosed |
| US-4233214-A | FOR POLYACRYLONITRILE AND ACID-MODIFIED POLYESTERS OR POLYAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-11-11 | — | — | US | disclosed |
| US-4036826-A | Cationic azo dyestuffs with a hydroxyalkylated ammonium group | BAYER AKTIENGESELLSCHAFT (DT) | 1977-07-19 | — | — | US | disclosed |