Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 8/20 | 0.47 |
| ▸ | HTR2A | P28223 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5636963 | 0.99 | HTR2C (0.46) | HTR2CHTR2AKDM4EMEN1TP53 | |
| SCHEMBL5636305 | 0.92 | HTR2C (0.48) | HTR2CHTR2AKDM4EMEN1TP53 | |
| SCHEMBL6852201 | 0.90 | HTR2C (0.58) | HTR2CHTR2AKDM4EMEN1TP53 | |
| Hydrochloric Acid SCHEMBL5636361 | 0.89 | HTR2C (0.56) | HTR2CHTR2AKDM4EMEN1TP53 | |
| Hydrochloric Acid SCHEMBL5637761 | 0.82 | HTR2C (0.54) | HTR2CHTR2AKDM4EMEN1TP53 | |
| SCHEMBL6493416 | 0.79 | HTR2C (0.54) | HTR2CHTR2AKDM4EMEN1TP53 | |
| Hydrochloric Acid SCHEMBL11430606 | 0.78 | HTR2C (0.53) | HTR2CHTR2AKDM4EMEN1TP53 | |
| SCHEMBL5428200 | 0.77 | HTR2C (0.62) | HTR2CHTR2AKDM4EMEN1TP53 | |
| SCHEMBL5636374 | 0.77 | HTR2C (0.36) | HTR2CHTR2AKDM4EMEN1TP53 | |
| Hydrochloric Acid SCHEMBL5424435 | 0.76 | HTR2C (0.60) | HTR2CHTR2AKDM4EMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4238607-A | ANTIBIOTICS, SEDATIVES, HYPOTENSIVE AGENTS, AND ANTIDEPRESSANTS | ENDO LABORATORIES INC. (US) | 1980-12-09 | — | — | US | disclosed |
| US-4183936-A | SEDATIVES, ANTIDEPRESSANTS, HYPOTENSIVE AGENTS, BACTERICIDES | ENDO LABORATORIES, INC. (US) | 1980-01-15 | — | — | US | disclosed |
| US-4115577-A | SEDATIVES, ANTIDEPRESSANT ANTIHYPERTENSIVE, ANTIBACTERIAL | ENDO LABORATORIES, INC. (US) | 1978-09-19 | — | — | US | disclosed |
| US-4013652-A | SEDATIVES | ENDO LABORATORIES, INC. (US) | 1977-03-22 | — | — | US | disclosed |