Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ATP4A | P20648 | 8/20 | 0.48 |
| ▸ | ATP4B | P51164 | 8/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15722636 | 0.83 | NPC1 (0.52) | NPC1RAB9AALDH1A1GAAATP4A | |
| SCHEMBL5677925 | 0.80 | NPC1 (0.52) | NPC1RAB9AALDH1A1GAAATP4A | |
| SCHEMBL18369556 | 0.79 | NPC1 (0.51) | NPC1RAB9AALDH1A1GAAATP4A | |
| SCHEMBL28659641 | 0.78 | NPC1 (0.48) | NPC1RAB9AALDH1A1GAAATP4A | |
| SCHEMBL23185863 | 0.78 | NPC1 (0.50) | NPC1RAB9AALDH1A1GAAATP4A | |
| SCHEMBL16705693 | 0.78 | NPC1 (0.50) | NPC1RAB9AALDH1A1GAAATP4A | |
| SCHEMBL15722637 | 0.78 | NPC1 (0.50) | NPC1RAB9AALDH1A1GAAATP4A | |
| SCHEMBL21664333 | 0.78 | NPC1 (0.50) | NPC1RAB9AALDH1A1GAAATP4A | |
| SCHEMBL15722747 | 0.78 | NPC1 (0.50) | NPC1RAB9AALDH1A1GAAATP4A | |
| SCHEMBL7090398 | 0.77 | GAA (0.61) | NPC1RAB9AALDH1A1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4238615-A | FOR USE IN PERFUMES | OTSUKA KAGAKU YAKUHIN KABUSHIKI KAISHA (JP) | 1980-12-09 | — | — | US | disclosed |