SCHEMBL16705693

SCHEMBL16705693

CCCCCCCN(N)c1nc2ccccc2s1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.50
RAB9A P51151 4/20 0.50
ALDH1A1 P00352 3/20 0.50
GAA P10253 1/20 0.45
ATP4A P20648 4/20 0.43
ATP4B P51164 4/20 0.43
TLR8 Q9NR97 2/20 0.43
SMN1; SMN2 Q16637 4/20 0.42
LMNA P02545 1/20 0.42
TP53 P04637 1/20 0.42
CASP3 P42574 1/20 0.42
SENP8 Q96LD8 1/20 0.42
SENP7 Q9BQF6 1/20 0.42
SENP6 Q9GZR1 1/20 0.42
ALOX15 P16050 1/20 0.42
TSHR P16473 1/20 0.42
HDAC1 Q13547 2/20 0.41
UBE2T Q9NPD8 1/20 0.41
ASIC3 Q9UHC3 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15722747 1.00 NPC1 (0.50) NPC1RAB9AALDH1A1GAAATP4A
SCHEMBL23185863 1.00 NPC1 (0.50) NPC1RAB9AALDH1A1GAAATP4A
SCHEMBL15722637 1.00 NPC1 (0.50) NPC1RAB9AALDH1A1GAAATP4A
SCHEMBL18369556 0.99 NPC1 (0.51) NPC1RAB9AALDH1A1GAAATP4A
SCHEMBL15722636 0.94 NPC1 (0.52) NPC1RAB9AALDH1A1GAAATP4A
SCHEMBL16851750 0.88 NPC1 (0.48) NPC1RAB9AALDH1A1GAAATP4A
SCHEMBL21675553 0.86 ILK (0.43) NPC1RAB9AALDH1A1GAASMN1; SMN2
SCHEMBL21413246 0.86 ILK (0.43) NPC1RAB9AALDH1A1GAASMN1; SMN2
SCHEMBL21675451 0.86 ILK (0.43) NPC1RAB9AALDH1A1GAASMN1; SMN2
SCHEMBL21233554 0.86 ILK (0.43) NPC1RAB9AALDH1A1GAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10968189-B2 Method for producing 2-hydrazinobenzothiazole derivative DIC CORPORATION (JP) 2021-04-06 US disclosed
US-10927087-B2 Method for producing polymerizable compound DIC CORPORATION (JP) 2021-02-23 US disclosed
US-20200165215-A1 METHOD FOR PRODUCING 2-HYDRAZINOBENZOTHIAZOLE DERIVATIVE DIC CORPORATION (JP) 2020-05-28 US disclosed
US-20190322872-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, OPTICAL FILM, OPTICALLY ANISOTROPIC BODY, POLARIZER, FLAT PANEL DISPLAY, ORGANIC ELECTROLUMINESCENCE DISPLAY, ANTIREFLECTION FILM, AND COMPOUND ZEON CORPORATION (JP) 2019-10-24 US disclosed
US-9643942-B2 Method for manufacturing 1,1-disubstituted hydrazine compound ZEON CORPORATION (JP) 2017-05-09 US disclosed
US-9643942-B2 Method for manufacturing 1,1-disubstituted hydrazine compound ZEON CORPORATION (JP) 2017-05-09 US disclosed
US-9586917-B2 Polymerizable compound, polymerizable composition, polymer, optically anisotropic body, and method for producing polymerizable compound ZEON CORPORATION (JP) 2017-03-07 US disclosed
US-9586917-B2 Polymerizable compound, polymerizable composition, polymer, optically anisotropic body, and method for producing polymerizable compound ZEON CORPORATION (JP) 2017-03-07 US disclosed
US-20170008862-A1 METHOD FOR MANUFACTURING 1,1-DISUBSTITUTED HYDRAZINE COMPOUND ZEON CORPORATION (JP) 2017-01-12 US disclosed
US-20170008862-A1 METHOD FOR MANUFACTURING 1,1-DISUBSTITUTED HYDRAZINE COMPOUND ZEON CORPORATION (JP) 2017-01-12 US disclosed
US-20160280672-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, OPTICALLY ANISOTROPIC BODY, AND METHOD FOR PRODUCING POLYMERIZABLE COMPOUND ZEON CORPORATION (JP) 2016-09-29 US disclosed
US-20160280672-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, OPTICALLY ANISOTROPIC BODY, AND METHOD FOR PRODUCING POLYMERIZABLE COMPOUND ZEON CORPORATION (JP) 2016-09-29 US disclosed
US-20150175564-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, OPTICALLY ANISOTROPIC BODY, AND METHOD FOR PRODUCING POLYMERIZABLE COMPOUND ZEON CORPORATION (JP) 2015-06-25 US disclosed
US-20150175564-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, OPTICALLY ANISOTROPIC BODY, AND METHOD FOR PRODUCING POLYMERIZABLE COMPOUND ZEON CORPORATION (JP) 2015-06-25 US disclosed
EP-2871192-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, OPTICALLY ANISOTROPIC BODY, AND METHOD FOR PRODUCING POLYMERIZABLE COMPOUND Zeon Corporation (JP) 2015-05-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190322872-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, OPTICAL FILM, OPTICALLY ANISOTROPIC BODY, POLARIZER, FLAT PANEL DISPLAY, ORGANIC ELECTROLUMINESCENCE DISPLAY, ANTIREFLECTION FILM, AND COMPOUND H1-0, H1-4, H1-10 NPC1 3463/4885RAB9A 3060/4885ALDH1A1 379/4885
US-20170008862-A1 METHOD FOR MANUFACTURING 1,1-DISUBSTITUTED HYDRAZINE COMPOUND HRH1, HBZ, H1-0 NPC1 2157/4885RAB9A 603/4885ALDH1A1 209/4885
US-20200165215-A1 METHOD FOR PRODUCING 2-HYDRAZINOBENZOTHIAZOLE DERIVATIVE HAO2, IDH2, HACL2 NPC1 2261/4885RAB9A 3845/4885ALDH1A1 159/4885
US-20160280672-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, OPTICALLY ANISOTROPIC BODY, AND METHOD FOR PRODUCING POLYMERIZABLE COMPOUND PYM1, C5, C1S NPC1 3672/4885RAB9A 3942/4885ALDH1A1 987/4885
US-10927087-B2 Method for producing polymerizable compound INCENP, INF2, INHA NPC1 4131/4885RAB9A 3222/4885ALDH1A1 693/4885
US-20150175564-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE COMPOSITION, POLYMER, OPTICALLY ANISOTROPIC BODY, AND METHOD FOR PRODUCING POLYMERIZABLE COMPOUND PYM1, C5, C1S NPC1 3672/4885RAB9A 3942/4885ALDH1A1 987/4885
US-10968189-B2 Method for producing 2-hydrazinobenzothiazole derivative HAO2, IDH2, HACL2 NPC1 2261/4885RAB9A 3845/4885ALDH1A1 159/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.