Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11428211 | 0.72 | ALDH1A1 (0.30) | ALDH1A1CYP3A4 | |
| SCHEMBL4966088 | 0.72 | — | — | |
| SCHEMBL10086842 | 0.72 | ALDH1A1 (0.30) | ALDH1A1CYP3A4 | |
| SCHEMBL8408673 | 0.72 | — | — | |
| Methane SCHEMBL11184882 | 0.70 | — | — | |
| SCHEMBL6445039 | 0.69 | — | — | |
| SCHEMBL18023461 | 0.68 | — | — | |
| SCHEMBL14601600 | 0.68 | — | — | |
| SCHEMBL14793076 | 0.66 | — | — | |
| SCHEMBL16467148 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4208533-A | Synthesis of cyclopentanol | HOFFMANN-LA ROCHE INC. (US) | 1980-06-17 | — | — | US | claimed |
| US-4208533-A | Synthesis of cyclopentanol | HOFFMANN-LA ROCHE INC. (US) | 1980-06-17 | — | — | US | disclosed |
| US-4159386-A | Synthesis of cyclopentanol | HOFFMANN-LA ROCHE INC. (US) | 1979-06-26 | — | — | US | disclosed |
| US-4154963-A | Prostaglandin intermediates | HOFFMANN-LA ROCHE INC. (US) | 1979-05-15 | — | — | US | disclosed |
| US-4089889-A | Synthesis of cyclopentanol | HOFFMANN-LA ROCHE INC. (US) | 1978-05-16 | — | — | US | disclosed |
| US-4074045-A | 2H-cyclopenta b!furan-2-ones and process for preparation | HOFFMANN-LA ROCHE INC. (US) | 1978-02-14 | — | — | US | disclosed |
| US-4070378-A | Synthesis cyclopentanol | HOFFMANN-LA ROCHE, INC. (US) | 1978-01-24 | — | — | US | disclosed |
| US-4059577-A | Synthesis of cyclopentanol | HOFFMANN-LA ROCHE, INC. (US) | 1977-11-22 | — | — | US | disclosed |
| US-4044005-A | Peroxides of 2-oxo-cyclopenta[b]furans | HOFFMANN-LA ROCHE INC. (US) | 1977-08-23 | — | — | US | disclosed |
| US-4032520-A | SYNTHESIS OF CYCLOPENTANOL | KIENZLE FRANK | 1977-06-28 | — | — | US | disclosed |
| US-4029674-A | 2-Oxo-2H cyclopenta[b]furans | HOFFMANN-LA ROCHE INC. (US) | 1977-06-14 | — | — | US | disclosed |
| US-4005110-A | 2H-Cyclopenta(b)furan-2-ones | HOFFMANN-LA ROCHE INC. (US) | 1977-01-25 | — | — | US | disclosed |
| US-4001281-A | 2-Oxo-cyclopenta[b]furan-5α-carboxylic acid esters | HOFFMANN-LA ROCHE INC. (US) | 1977-01-04 | — | — | US | disclosed |