Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA3 | P07451 | 1/20 | 0.57 |
| ▸ | CA6 | P23280 | 1/20 | 0.57 |
| ▸ | CA5A | P35218 | 1/20 | 0.57 |
| ▸ | CA7 | P43166 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.57 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11423923 | 0.90 | SLC16A3 (0.57) | MAPTKDM4EALDH1A1HPGDCA12 | |
| SCHEMBL11494798 | 0.85 | MAOB (0.61) | MAPTKDM4EALDH1A1HPGDCA12 | |
| SCHEMBL11402397 | 0.81 | MAPT (0.67) | MAPTKDM4EALDH1A1HPGDCA12 | |
| SCHEMBL11396182 | 0.79 | MAPT (0.63) | MAPTKDM4EALDH1A1HPGDCA12 | |
| SCHEMBL11485323 | 0.79 | MAPT (0.60) | MAPTKDM4EALDH1A1HPGDCA12 | |
| SCHEMBL11485319 | 0.79 | MAPT (0.60) | MAPTKDM4EALDH1A1HPGDCA12 | |
| SCHEMBL11397132 | 0.78 | MAPT (0.70) | MAPTKDM4EALDH1A1HPGDCA12 | |
| SCHEMBL11425574 | 0.76 | KDM4E (0.61) | MAPTKDM4EALDH1A1HPGDCA12 | |
| SCHEMBL11416012 | 0.75 | CA12 (0.58) | MAPTKDM4EALDH1A1HPGDCA12 | |
| SCHEMBL29963204 | 0.73 | KDM4E (1.00) | MAPTKDM4EALDH1A1HPGDCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4210758-A | 1,5-Dihydro-1,5-dioxo-N-1H-tetrazol-5-yl-4H-[1]benzopyrano[3,4-b]pyridine-2-carboxamides | WARNER-LAMBERT COMPANY (US) | 1980-07-01 | — | — | US | disclosed |