Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | HPGD | P15428 | 6/20 | 0.54 |
| ▸ | GAA | P10253 | 5/20 | 0.54 |
| ▸ | MAOB | P27338 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.54 |
| ▸ | GLA | P06280 | 5/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 3/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA3 | P07451 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11429014 | 0.90 | MAPT (0.60) | ALDH1A1HPGDGAAMAOBKDM4E | |
| SCHEMBL11425574 | 0.85 | KDM4E (0.61) | SLC16A3ALDH1A1HPGDGAAMAOB | |
| SCHEMBL30488625 | 0.82 | GLA (0.62) | SLC16A3ALDH1A1HPGDGAAMAOB | |
| SCHEMBL11402546 | 0.81 | SLC16A3 (0.61) | SLC16A3ALDH1A1HPGDGAAMAOB | |
| SCHEMBL3100581 | 0.81 | SLC16A3 (0.64) | SLC16A3ALDH1A1HPGDGAAMAOB | |
| SCHEMBL11395960 | 0.79 | ALDH1A1 (0.61) | SLC16A3ALDH1A1HPGDGAAMAOB | |
| SCHEMBL11396698 | 0.78 | ALDH1A1 (0.78) | SLC16A3ALDH1A1HPGDGAAMAOB | |
| SCHEMBL11494798 | 0.76 | MAOB (0.61) | ALDH1A1HPGDGAAMAOBKDM4E | |
| SCHEMBL11416012 | 0.75 | CA12 (0.58) | ALDH1A1HPGDKDM4EHSD17B10NPC1 | |
| SCHEMBL11612554 | 0.75 | PTGS2 (0.52) | ALDH1A1HPGDMAOBKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4210758-A | 1,5-Dihydro-1,5-dioxo-N-1H-tetrazol-5-yl-4H-[1]benzopyrano[3,4-b]pyridine-2-carboxamides | WARNER-LAMBERT COMPANY (US) | 1980-07-01 | — | — | US | disclosed |