Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11428389 | 0.89 | PTPRC (0.41) | PTPRCEGFRGAARXRARXRB | |
| SCHEMBL11431587 | 0.80 | MAPT (0.43) | SMN1; SMN2AKR1C3AKR1C2CYP1A2KDM4E | |
| SCHEMBL11429420 | 0.77 | GAA (0.49) | SMN1; SMN2TSHREGFRPGRKDM4E | |
| SCHEMBL11425973 | 0.76 | EGFR (0.46) | SMN1; SMN2EGFRPGRKDM4EALDH1A1 | |
| SCHEMBL11429789 | 0.73 | EGFR (0.44) | EGFRPGRKDM4EALDH1A1GAA | |
| SCHEMBL11435913 | 0.73 | EGFR (0.44) | EGFRPGRKDM4EALDH1A1GAA | |
| SCHEMBL11429371 | 0.73 | EGFR (0.44) | SMN1; SMN2EGFRPGRKDM4EALDH1A1 | |
| SCHEMBL11551182 | 0.73 | CYP1A2 (0.48) | SMN1; SMN2CYP1A2KDM4EALDH1A1GAA | |
| SCHEMBL11428785 | 0.72 | EGFR (0.44) | PTPRCEGFRPGRKDM4EALDH1A1 | |
| SCHEMBL11428500 | 0.72 | EGFR (0.46) | EGFRCYP1A2PGRKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4235619-A | USING 3-PHENYL-4(1H)-PYRIDONES OR PYRIDINETHIONES | ELI LILLY AND COMPANY (US) | 1980-11-25 | — | — | US | disclosed |
| US-4152136-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1979-05-01 | — | — | US | disclosed |