Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11429280 | 0.89 | PTPRC (0.37) | PTPRCGAAEGFRRXRARXRB | |
| SCHEMBL11429420 | 0.89 | GAA (0.49) | BRD4MEN1KMT2AGAAMAPT | |
| SCHEMBL11551182 | 0.86 | CYP1A2 (0.48) | BRD4CNR1MEN1KMT2AGAA | |
| SCHEMBL11441314 | 0.86 | BRD4 (0.52) | BRD4CREBBPHSD17B10GAAMAPT | |
| SCHEMBL11431671 | 0.83 | EGFR (0.50) | MEN1KMT2AGAAEGFR | |
| SCHEMBL11547644 | 0.82 | BRD4 (0.48) | BRD4CREBBPHSD17B10MEN1KMT2A | |
| SCHEMBL11550436 | 0.82 | CYP2A6 (0.41) | BRD4CREBBPMAPTHTTNR1H2 | |
| SCHEMBL11550186 | 0.81 | HSD11B1 (0.50) | HSD17B10CNR1MEN1KMT2AMAPT | |
| SCHEMBL11429053 | 0.81 | GSK3B (0.42) | BRD4CNR2MEN1KMT2ARXFP1 | |
| SCHEMBL11426297 | 0.81 | BRD9 (0.53) | BRD4CREBBPHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4235619-A | USING 3-PHENYL-4(1H)-PYRIDONES OR PYRIDINETHIONES | ELI LILLY AND COMPANY (US) | 1980-11-25 | — | — | US | disclosed |
| US-4152136-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1979-05-01 | — | — | US | disclosed |