Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10603096 | 1.00 | CYP1A2 (0.39) | CYP1A2LMNAMAPK1HTTCYP2C9 | |
| SCHEMBL8977251 | 0.88 | CYP1A2 (0.54) | CYP1A2LMNAMAPK1HTTCYP2C9 | |
| SCHEMBL8977298 | 0.85 | CYP1A2 (0.50) | CYP1A2LMNAMAPK1HTTCYP2C9 | |
| SCHEMBL11144783 | 0.80 | — | — | |
| SCHEMBL129995 | 0.79 | — | — | |
| SCHEMBL5691374 | 0.79 | CYP1A2 (0.48) | CYP1A2LMNAMAPK1HTTCYP2C9 | |
| SCHEMBL8417237 | 0.76 | CYP1A2 (0.39) | CYP1A2LMNAMAPK1HTTCYP2C9 | |
| SCHEMBL21220108 | 0.76 | CYP1A2 (0.34) | CYP1A2LMNAMAPK1CYP2C9MAPT | |
| SCHEMBL8417235 | 0.76 | CYP1A2 (0.39) | CYP1A2LMNAMAPK1HTTCYP2C9 | |
| Ammonia Solution, Strong SCHEMBL267680 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2212308-B1 | BENZO[F]CHROME AND PYRANO[3,2-F]CHROME DERIVATIVES FOR USE IN LIQUID CRYSTAL MEDIA | MERCK PATENT GMBH (DE) | 2013-05-22 | — | — | EP | disclosed |
| US-8303844-B2 | Benzo[f]chrome any pyrano[3,2-f]chrome derivatives for use in liquid crystal media | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-11-06 | — | — | US | disclosed |
| US-20110043746-A1 | BENZO[F]CHROME ANY PYRANO[3,2-F]CHROME DERIVATIVES FOR USE IN LIQUID CRYSTAL MEDIA | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-02-24 | — | — | US | disclosed |
| EP-2212308-A1 | BENZO[F]CHROME AND PYRANO[3,2-F]CHROME DERIVATIVES FOR USE IN LIQUID CRYSTAL MEDIA | Merck Patent GmbH (DE) | 2010-08-04 | — | — | EP | disclosed |
| WO-2009068152-A1 | BENZO[F]CHROME AND PYRANO[3,2-F]CHROME DERIVATIVES FOR USE IN LIQUID CRYSTAL MEDIA | MERCK PATENT GMBH (DE) | 2009-06-04 | — | — | WO | disclosed |
| US-5523439-A | Process for preparing silacyclohexane compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0696592-A1 | Process for preparing silacyclohexane compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |
| US-4868341-A | LIQUID CRYSTALS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-09-19 | — | — | US | disclosed |
| EP-0198714-B1 | LIQUID CRISTALLINE COMPOSITIONS CONTAINING CYCLOHEXYLCYCLOHEXENE DERIVATIVES, AND THEIR USE | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1989-08-09 | — | — | EP | disclosed |
| US-4698177-A | LOW VISCOSITY LIQUID CRYSTALS | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1987-10-06 | — | — | US | disclosed |
| US-4622164-A | LIQUID CRYSTAL DIELECTRICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1986-11-11 | — | — | US | disclosed |
| EP-0198714-A1 | Liquid cristalline compositions containing cyclohexylcyclohexene derivatives, and their use | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1986-10-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110043746-A1 | BENZO[F]CHROME ANY PYRANO[3,2-F]CHROME DERIVATIVES FOR USE IN LIQUID CRYSTAL MEDIA | CHRM1, F12, CTRB2 | CYP1A2 99/4885LMNA 132/4885MAPK1 435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.