SCHEMBL11429565

SCHEMBL11429565

O=C(OCC1CO1)C(Cl)Cl

nearest known ligand 0.50

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.50
TP53 P04637 1/20 0.50
CYP3A4 P08684 1/20 0.50
MGLL Q99685 4/20 0.39
TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22689592 0.83 ALDH1A1 (0.52) ALDH1A1TP53CYP3A4MGLLTSHR
SCHEMBL8750994 0.80 ALDH1A1 (0.52) ALDH1A1TP53CYP3A4MGLLTSHR
SCHEMBL92977 0.78 ALDH1A1 (0.55) ALDH1A1TP53CYP3A4MGLLTSHR
SCHEMBL16687820 0.78 ALDH1A1 (0.55) ALDH1A1TP53CYP3A4MGLLTSHR
SCHEMBL314330 0.77
SCHEMBL5247142 0.77 ALDH1A1 (0.53) ALDH1A1TP53CYP3A4MGLLTSHR
SCHEMBL543862 0.77 ALDH1A1 (0.69) ALDH1A1TP53CYP3A4MGLLTSHR
SCHEMBL377540 0.77 ALDH1A1 (0.57) ALDH1A1TP53CYP3A4MGLLTSHR
SCHEMBL22657946 0.76 ALDH1A1 (0.52) ALDH1A1TP53CYP3A4MGLLTSHR
SCHEMBL23466921 0.75 ALDH1A1 (0.47) ALDH1A1TP53CYP3A4MGLLTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4211850-A Polyhydroxy compounds containing urethane aryl sulfonic acid hydroxyalkyl ester groups BAYER AKTIENGESELLSCHAFT (DE) 1980-07-08 US disclosed
US-4201852-A Polyurethanes based on modified polyisocyanates containing sulphonic acid ester groups and process for the production thereof BAYER AKTIENGESELLSCHAFT (DE) 1980-05-06 US disclosed
US-4189562-A Polyhydroxy compounds containing urethane aryl sulfonic acid hydroxyalkyl ester groups BAYER AKTIENGESELLSCHAFT (DE) 1980-02-19 US disclosed