Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TOP1 | P11387 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11422156 | 0.93 | SMN1; SMN2 (0.49) | MEN1KMT2AGAAPOLBLMNA | |
| SCHEMBL11424194 | 0.86 | CD40 (0.52) | MEN1KMT2AGAAPOLBLMNA | |
| SCHEMBL11430329 | 0.85 | MEN1 (0.53) | MEN1KMT2AGAAPOLBLMNA | |
| SCHEMBL11430473 | 0.85 | KMT2A (0.44) | MEN1KMT2AGAALMNAMAPT | |
| SCHEMBL11431853 | 0.85 | KMT2A (0.47) | MEN1KMT2APOLBMAPTRAB9A | |
| SCHEMBL11428520 | 0.84 | TOP1 (0.42) | MEN1KMT2AMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL11422158 | 0.83 | KMT2A (0.44) | MEN1KMT2AGAAPOLBLMNA | |
| SCHEMBL11425015 | 0.82 | TOP1 (0.42) | MEN1KMT2AMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL11422040 | 0.81 | MEN1 (0.55) | MEN1KMT2AGAAPOLBLMNA | |
| SCHEMBL11434112 | 0.80 | TOP1 (0.43) | MEN1KMT2AGAAPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216166-A | Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |