Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 3/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MLNR | O43193 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11422158 | 0.93 | KMT2A (0.44) | KMT2AALDH1A1KCNMA1HPGDKDM4E | |
| SCHEMBL11428526 | 0.86 | KDM4E (0.38) | KMT2AALDH1A1KCNMA1HPGDKDM4E | |
| SCHEMBL11430336 | 0.85 | KCNMA1 (0.48) | KMT2AALDH1A1KCNMA1HPGDKDM4E | |
| SCHEMBL11430469 | 0.85 | MEN1 (0.48) | KMT2AALDH1A1KDM4EMAPTHTT | |
| Acetic Acid SCHEMBL11430476 | 0.85 | ALDH1A1 (0.46) | KMT2AALDH1A1KCNMA1HPGDKDM4E | |
| SCHEMBL11422156 | 0.83 | SMN1; SMN2 (0.49) | KMT2AALDH1A1HPGDMAPTHTT | |
| SCHEMBL11425022 | 0.82 | KDM4E (0.36) | KMT2AALDH1A1KCNMA1HPGDKDM4E | |
| SCHEMBL11422042 | 0.81 | KCNMA1 (0.48) | KMT2AALDH1A1KCNMA1HPGDKDM4E | |
| SCHEMBL11424194 | 0.81 | CD40 (0.52) | KMT2AALDH1A1KDM4EMAPTHTT | |
| SCHEMBL11433711 | 0.80 | KCNMA1 (0.44) | KMT2AALDH1A1KCNMA1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216166-A | Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |