⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4374658 | 0.61 | — | — | |
| SCHEMBL7877974 | 0.60 | — | — | |
| SCHEMBL17703988 | 0.57 | MEN1 (0.30) | — | |
| SCHEMBL6406378 | 0.57 | — | — | |
| SCHEMBL7040068 | 0.56 | — | — | |
| SCHEMBL4832607 | 0.54 | — | — | |
| SCHEMBL6549885 | 0.51 | — | — | |
| SCHEMBL3174810 | 0.51 | HTR6 (0.31) | — | |
| SCHEMBL8170698 | 0.49 | HTR6 (0.30) | — | |
| SCHEMBL8170693 | 0.49 | HTR6 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4224334-A | Antiinflammatory imidazothiazoles and thiazolopyrimidines | DIAMOND SHAMROCK CORPORATION (US) | 1980-09-23 | — | — | US | disclosed |
| US-4160768-A | Anti-inflammatory 3-benzofuranyl imidazothiazole | DIAMOND SHAMROCK CORPORATION (US) | 1979-07-10 | — | — | US | disclosed |
| US-4110451-A | ANTIINFLAMMATORY IMIDAZOTHIAZOLES AND THIAZOLOPYRIMIDINES | DIAMOND SHAMROCK CORPORATION (US) | 1978-08-29 | — | — | US | disclosed |
| US-4103016-A | Antiinflammatory imidazothiazoles and thiazolopyrimidines | DIAMOND SHAMROCK CORPORATION (US) | 1978-07-25 | — | — | US | disclosed |
| US-4041167-A | INHIBITING FORMATION OF GRANULOMA TISSUE | DIAMOND SHAMROCK CORPORATION (US) | 1977-08-09 | — | — | US | disclosed |