Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 17/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9468394 | 0.80 | CTSA (0.43) | CTSAL3MBTL1POLBHTTNPSR1 | |
| SCHEMBL658439 | 0.79 | GABBR2 (0.48) | CTSAL3MBTL1POLBHTTNPSR1 | |
| SCHEMBL30781885 | 0.79 | GABBR2 (0.48) | CTSAL3MBTL1POLBHTTNPSR1 | |
| SCHEMBL8407354 | 0.77 | POLB (0.49) | L3MBTL1POLBHTTNPSR1SMN1; SMN2 | |
| SCHEMBL18150761 | 0.76 | POLB (0.73) | CTSAL3MBTL1POLBHTTNPSR1 | |
| SCHEMBL30781902 | 0.76 | POLB (0.73) | CTSAL3MBTL1POLBHTTNPSR1 | |
| SCHEMBL19143619 | 0.76 | GAA (0.51) | L3MBTL1POLBHTTNPSR1SMN1; SMN2 | |
| SCHEMBL1261369 | 0.76 | KMT2A (0.44) | CTSAL3MBTL1POLBHTTNPSR1 | |
| SCHEMBL657343 | 0.74 | CTSA (0.42) | CTSAL3MBTL1POLBHTTNPSR1 | |
| SCHEMBL2794839 | 0.73 | CTSA (0.49) | CTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4221725-A | CHEMICAL INTERMEDIATE | E. R. SQUIBB & SONS, INC. (US) | 1980-09-09 | — | — | US | disclosed |