Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11439758 | 0.80 | TAAR1 (0.40) | TAAR1SLC6A2SLC6A3SLC6A4CYP2D6 | |
| SCHEMBL4136824 | 0.68 | BACE1 (1.00) | BACE1TAAR1SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL5335894 | 0.66 | GAA (0.52) | BACE1SLC6A2SLC6A3SLC6A4CYP2D6 | |
| SCHEMBL7814746 | 0.66 | BACE1 (0.51) | BACE1SLC6A2SLC6A3SLC6A4CYP2D6 | |
| SCHEMBL5542785 | 0.64 | TAAR1 (0.43) | BACE1TAAR1SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL657183 | 0.64 | SLC6A2 (0.44) | BACE1TAAR1SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL734590 | 0.63 | PDE4A (0.47) | BACE1SLC6A2SLC6A3SLC6A4CYP2D6 | |
| SCHEMBL5580256 | 0.63 | TDP1 (0.56) | BACE1SLC6A2SLC6A3SLC6A4CYP2D6 | |
| SCHEMBL9864166 | 0.63 | SLC6A2 (0.46) | BACE1TAAR1SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL14833300 | 0.63 | PDE4A (0.47) | BACE1SLC6A2SLC6A3SLC6A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0007019-A1 | 5-Phenyl-pyrazole derivatives and their salts, processes for their preparation and medicines containing them | Kali-Chemie Pharma GmbH (DE) | 1980-01-23 | — | — | EP | disclosed |