Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.37 |
| ▸ | USP36 | Q9P275 | 1/20 | 0.37 |
| ▸ | GPR183 | P32249 | 2/20 | 0.36 |
| ▸ | PDE2A | O00408 | 2/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11433927 | 0.84 | KIF11 (0.34) | CYP3A4CYP17A1CYP2C9CYP2C19CYP19A1 | |
| SCHEMBL11439081 | 0.73 | CNR1 (0.36) | GPR183PDE2ACYP19A1 | |
| SCHEMBL11445417 | 0.73 | CYP19A1 (0.60) | USP36GPR183PDE2ACYP17A1CYP19A1 | |
| SCHEMBL11727418 | 0.71 | CYP19A1 (0.40) | CYP3A4PDE2ACYP19A1 | |
| SCHEMBL15686089 | 0.70 | CYP19A1 (0.62) | CYP3A4CYP17A1CYP19A1 | |
| SCHEMBL125811 | 0.69 | CYP19A1 (0.61) | CYP3A4CYP17A1CYP19A1 | |
| SCHEMBL2662891 | 0.68 | PDE2A (0.43) | GPR183PDE2A | |
| SCHEMBL11445538 | 0.68 | CYP19A1 (0.44) | GPR183PDE2ACYP17A1CYP19A1 | |
| SCHEMBL14234750 | 0.67 | CYP19A1 (0.38) | CYP3A4CYP17A1CYP19A1 | |
| SCHEMBL69378 | 0.67 | CYP3A4 (0.42) | CYP3A4CYP17A1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3967949-A | Fluoroalkoxyphenyl-substituted nitrogen heterocycles as plant stunting agents | ELI LILLY AND COMPANY (US) | 1976-07-06 | — | — | US | claimed |
| US-4194899-A | HERBICIDES, FUNGICIDES, PLANT GROWTH REGULATORS | ELI LILLY AND COMPANY (US) | 1980-03-25 | — | — | US | disclosed |
| US-4110099-A | INHIBITOR FOR INTERNODEL GROWTH OF PLANTS | ELI LILLY AND COMPANY (US) | 1978-08-29 | — | — | US | disclosed |
| US-RE29367-E | HERBICIDES, FUNGICIDES, 5-PYRIMIDINYL | ELI LILLY AND COMPANY (US) | 1977-08-23 | — | — | US | disclosed |
| US-4002628-A | HERBICIDES, PLANT FUNGICIDES, PLANT GROWTH REGULATORS | ELI LILLY AND COMPANY (US) | 1977-01-11 | — | — | US | disclosed |
| US-3967949-A | Fluoroalkoxyphenyl-substituted nitrogen heterocycles as plant stunting agents | ELI LILLY AND COMPANY (US) | 1976-07-06 | — | — | US | disclosed |