Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 9/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | PGR | P06401 | 4/20 | 0.60 |
| ▸ | AR | P10275 | 2/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.60 |
| ▸ | NR3C2 | P08235 | 7/20 | 0.59 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11424200 | 0.99 | NR3C2 (0.60) | HIF1AKMT2APGRARCHRM1 | |
| SCHEMBL11421975 | 0.97 | PGR (0.61) | HIF1AKMT2APGRARCHRM1 | |
| SCHEMBL11424725 | 0.95 | PGR (0.63) | HIF1AKMT2APGRARCHRM1 | |
| SCHEMBL11431262 | 0.94 | HIF1A (0.61) | HIF1AKMT2APGRARCHRM1 | |
| SCHEMBL11437616 | 0.93 | NR3C2 (0.60) | HIF1AKMT2APGRARCHRM1 | |
| SCHEMBL11425586 | 0.92 | NR3C2 (0.61) | HIF1AKMT2APGRARCHRM1 | |
| SCHEMBL11437044 | 0.91 | PGR (0.61) | HIF1AKMT2APGRARCHRM1 | |
| SCHEMBL11431440 | 0.90 | HIF1A (0.66) | HIF1AKMT2APGRARCHRM1 | |
| SCHEMBL11430689 | 0.89 | PGR (0.65) | HIF1AKMT2APGRARCHRM1 | |
| SCHEMBL11441908 | 0.88 | NR3C2 (0.65) | HIF1AKMT2APGRARCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4242334-A | ANTIINFLAMMATORY AGENTS; SKIN DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-12-30 | — | — | US | disclosed |