Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 7/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11444316 | 0.98 | MAPT (0.53) | MAPTL3MBTL1TDP1S1PR4MRGPRX4 | |
| SCHEMBL8535069 | 0.98 | MAPT (0.53) | MAPTL3MBTL1TDP1S1PR4MRGPRX4 | |
| SCHEMBL8902457 | 0.98 | MAPT (0.53) | MAPTL3MBTL1TDP1S1PR4MRGPRX4 | |
| SCHEMBL8536556 | 0.98 | MAPT (0.53) | MAPTL3MBTL1TDP1S1PR4MRGPRX4 | |
| SCHEMBL8539012 | 0.98 | MAPT (0.53) | MAPTL3MBTL1TDP1S1PR4MRGPRX4 | |
| SCHEMBL11565117 | 0.95 | MAPT (0.51) | MAPTL3MBTL1TDP1S1PR4MRGPRX4 | |
| SCHEMBL8903264 | 0.90 | MAPT (0.60) | MAPTL3MBTL1TDP1S1PR4MRGPRX4 | |
| SCHEMBL8536746 | 0.86 | MAPT (0.53) | MAPTL3MBTL1TDP1S1PR4HPGD | |
| SCHEMBL9217899 | 0.85 | MAPT (0.54) | MAPTL3MBTL1TDP1S1PR4MRGPRX4 | |
| SCHEMBL11353797 | 0.84 | S1PR4 (0.50) | MAPTL3MBTL1TDP1S1PR4MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4217346-A | Arylalkyl and aryloxyalkyl phosphonates as antiviral agents | STERLING DRUG INC. (US) | 1980-08-12 | — | — | US | disclosed |
| US-4182759-A | Arylalkyl and aryloxyalkyl phosphonates and use as antiviral agents | STERLING DRUG INC. (US) | 1980-01-08 | — | — | US | disclosed |