Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 18/20 | 0.54 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | PNP | P00491 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL122310 | 0.84 | JAK2 (0.57) | TYMPJAK2THRB | |
| Hydrochloric Acid SCHEMBL11433334 | 0.82 | JAK2 (0.55) | TYMPJAK2THRB | |
| SCHEMBL1224786 | 0.77 | TYMP (0.45) | TYMPJAK2THRB | |
| SCHEMBL12900039 | 0.73 | JAK2 (0.41) | TYMPJAK2THRB | |
| SCHEMBL1690954 | 0.70 | TYMP (1.00) | TYMPPNP | |
| SCHEMBL6570517 | 0.70 | TYMP (0.53) | TYMP | |
| SCHEMBL11425204 | 0.69 | TYMP (0.59) | TYMP | |
| SCHEMBL28448729 | 0.69 | TYMP (0.56) | TYMP | |
| SCHEMBL11431884 | 0.68 | TYMP (0.60) | TYMP | |
| SCHEMBL3114362 | 0.67 | DAO (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4202900-A | Derivatives of penam-3-carboxylic acid and a pharmaceutical composition containing the same | CIBA-GEIGY CORPORATION (US) | 1980-05-13 | — | — | US | disclosed |
| US-4045556-A | ANTIDEPRESSANTS, PYSCHOSTIMULANTS; SILYLATION | SCHWERTNER EBERHARD | 1977-08-30 | — | — | US | disclosed |
| US-4015000-A | 6-Acylamino-penam-3-carboxylic and 7-acylamino-3-cephem-4-carboxylic acids | CIBA-GEIGY CORPORATION (US) | 1977-03-29 | — | — | US | disclosed |