Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.73 |
| ▸ | MEN1 | O00255 | 3/20 | 0.73 |
| ▸ | POLB | P06746 | 3/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.73 |
| ▸ | RAB9A | P51151 | 3/20 | 0.73 |
| ▸ | RECQL | P46063 | 2/20 | 0.73 |
| ▸ | AHR | P35869 | 1/20 | 0.73 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.73 |
| ▸ | RAD52 | P43351 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.67 |
| ▸ | HTT | P42858 | 2/20 | 0.67 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.67 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.67 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | TERT | O14746 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6272682 | 0.85 | MAPT (0.73) | MAPTMEN1POLBKMT2ARAB9A | |
| SCHEMBL11442040 | 0.85 | MAPT (0.73) | MAPTMEN1POLBKMT2ARAB9A | |
| SCHEMBL11434901 | 0.84 | MAPT (0.69) | MAPTMEN1POLBKMT2ARAB9A | |
| SCHEMBL11434599 | 0.84 | MAPT (0.72) | MAPTMEN1POLBKMT2ARAB9A | |
| SCHEMBL19529498 | 0.82 | MAPT (0.70) | MAPTMEN1POLBKMT2ARAB9A | |
| SCHEMBL11434790 | 0.81 | RAD52 (1.00) | MAPTMEN1POLBKMT2ARAB9A | |
| Pinafide SCHEMBL18697 | 0.81 | MEN1 (1.00) | MAPTMEN1POLBKMT2ARAB9A | |
| SCHEMBL11441489 | 0.80 | KMT2A (0.64) | MAPTMEN1POLBKMT2ARAB9A | |
| SCHEMBL11552380 | 0.80 | MEN1 (0.98) | MAPTMEN1POLBKMT2ARAB9A | |
| SCHEMBL14560566 | 0.79 | HDAC3 (0.56) | MAPTMEN1POLBKMT2ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4204063-A | ANTITUMOR AGENTS | LABORATORIOS MADE, S.A. (ES) | 1980-05-20 | — | — | US | disclosed |