Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | POLB | P06746 | 3/20 | 0.64 |
| ▸ | RAB9A | P51151 | 3/20 | 0.64 |
| ▸ | RECQL | P46063 | 2/20 | 0.64 |
| ▸ | AHR | P35869 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | RAD52 | P43351 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.59 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.59 |
| ▸ | KLK7 | P49862 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11447384 | 0.87 | RAD52 (0.60) | KMT2AMAPTMEN1POLBRAB9A | |
| SCHEMBL14557208 | 0.83 | KLK7 (0.57) | KMT2AMAPTMEN1POLBAHR | |
| SCHEMBL11440392 | 0.82 | FTO (0.71) | KMT2AMAPTMEN1POLBAHR | |
| SCHEMBL8395426 | 0.81 | SIRT1 (0.65) | MAPTKLK7RXFP1CYP1A2CYP3A4 | |
| SCHEMBL3851575 | 0.81 | KMT2A (0.67) | KMT2AMAPTMEN1POLBKDM4E | |
| SCHEMBL5123962 | 0.81 | KDM4E (0.64) | KMT2AMAPTMEN1KDM4EKLK7 | |
| SCHEMBL10720844 | 0.80 | HEXA (0.57) | KDM4EHTTKLK7FTOGAA | |
| SCHEMBL11433686 | 0.80 | MAPT (0.73) | KMT2AMAPTMEN1POLBRAB9A | |
| SCHEMBL11434901 | 0.80 | MAPT (0.69) | KMT2AMAPTMEN1POLBRAB9A | |
| SCHEMBL8668083 | 0.80 | KLK7 (0.53) | KMT2AMAPTMEN1POLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4204063-A | ANTITUMOR AGENTS | LABORATORIOS MADE, S.A. (ES) | 1980-05-20 | — | — | US | disclosed |