Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CD40 | P25942 | 1/20 | 0.53 |
| ▸ | CD40LG | P29965 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.51 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.51 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.51 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.51 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11431680 | 0.90 | NPC1 (0.57) | KMT2AMEN1MAPTTDP1RAB9A | |
| SCHEMBL11434698 | 0.89 | CD40 (0.66) | KMT2AMEN1MAPTTDP1RAB9A | |
| SCHEMBL11425155 | 0.87 | KMT2A (0.57) | KMT2AMEN1MAPTTDP1RAB9A | |
| SCHEMBL11425321 | 0.86 | KMT2A (0.56) | KMT2AMEN1MAPTTDP1RAB9A | |
| SCHEMBL11429118 | 0.86 | NPC1 (0.57) | KMT2AMEN1MAPTTDP1RAB9A | |
| SCHEMBL11425137 | 0.85 | KMT2A (0.57) | KMT2AMEN1MAPTTDP1RAB9A | |
| SCHEMBL11426141 | 0.85 | KMT2A (0.63) | KMT2AMEN1MAPTTDP1RAB9A | |
| SCHEMBL11433874 | 0.84 | KMT2A (0.56) | KMT2AMEN1MAPTTDP1RAB9A | |
| SCHEMBL11500868 | 0.84 | KMT2A (0.65) | KMT2AMEN1MAPTTDP1RAB9A | |
| SCHEMBL11425328 | 0.84 | RAB9A (0.61) | KMT2AMEN1MAPTTDP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4216166-A | Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction | AMERICAN CYANAMID COMPANY (US) | 1980-08-05 | — | — | US | disclosed |