Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.49 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11433347 | 0.95 | POLB (0.61) | POLBL3MBTL1CHRM2CHRM4CHRM1 | |
| SCHEMBL21662979 | 0.85 | POLB (0.58) | POLBL3MBTL1CHRM2CHRM4CHRM1 | |
| SCHEMBL12975402 | 0.79 | POLB (0.58) | POLBL3MBTL1CHRM2CHRM4CHRM1 | |
| SCHEMBL15808670 | 0.79 | POLB (0.58) | POLBL3MBTL1CHRM2CHRM4CHRM1 | |
| SCHEMBL4124880 | 0.78 | MEN1 (0.57) | POLBL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL4778287 | 0.77 | L3MBTL1 (0.67) | POLBL3MBTL1CHRM2CHRM4CHRM1 | |
| SCHEMBL6293568 | 0.77 | POLB (0.61) | POLBL3MBTL1CHRM2CHRM4CHRM1 | |
| SCHEMBL11892686 | 0.77 | POLB (0.61) | POLBL3MBTL1CHRM2CHRM4CHRM1 | |
| SCHEMBL11892689 | 0.77 | POLB (0.61) | POLBL3MBTL1CHRM2CHRM4CHRM1 | |
| SCHEMBL30484008 | 0.77 | POLB (0.61) | POLBL3MBTL1CHRM2CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4206122-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1980-06-03 | — | — | US | disclosed |